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Table 2 Multivariable-adjusted HRs (95% CIs) and PAR% (95% CIs) for T2DM events by low-risk lifestyle factors

From: Association of healthy lifestyle including a healthy sleep pattern with incident type 2 diabetes mellitus among individuals with hypertension

Category

No. of participantsa

Cases/PYs (1000)b

HR (95% CI)c

Risk difference (%)

PAR% (95%CI)

Hypertension

 BMI

56,608

0.83

0.29 (0.26–0.33)

70.80

65.32 (61.96–68.38)

 Alcohol consumption

108,626

2.36

0.82 (0.77–0.87)

18.25

10.71 (7.52–13.79)

 Smoking status

121,704

2.23

0.77 (0.72–0.82)

23.00

13.40 (10.38–16.31)

 Physical activity

156,717

2.30

0.70 (0.66–0.75)

29.79

11.42 (9.62–13.18)

 Diet score

27,772

2.33

0.96 (0.86–1.07)

4.11

3.68 (-5.82–12.33)

 Sleep pattern

65,552

1.93

0.74 (0.69–0.80)

25.51

18.81 (14.72–22.70)

 Per unit increase in healthy lifestyle score

NA

NA

0.70 (0.68–0.72)

29.67

NA

Normotension

 BMI

90,976

0.28

0.26 (0.22–0.31)

73.97

63.33 (59.29–66.96)

 Alcohol consumption

103,622

0.74

0.80 (0.71–0.90)

19.97

11.06 (5.45–16.34)

 Smoking status

116,793

0.65

0.80 (0.70–0.90)

20.32

11.25 (5.63–16.55)

 Physical activity

146,193

0.71

0.74 (0.65–0.84)

26.28

9.33 (5.94–12.60)

 Diet score

26,502

0.58

0.72 (0.58–0.89)

28.09

25.61 (10.27–38.33)

 Sleep pattern

68,672

0.57

0.72 (0.63–0.83)

27.57

19.76 (12.47–26.45)

 Per unit increase in healthy lifestyle score

NA

NA

0.65 (0.62–0.68)

35.08

NA

All participants

 BMI

147,584

0.49

0.25 (0.23–0.28)

74.90

68.00 (65.70–70.14)

 Alcohol consumption

212,249

1.57

0.79 (0.75–0.84)

20.61

11.94 (9.26–14.54)

 Smoking status

238,497

1.45

0.78 (0.74–0.83)

21.59

12.44 (9.78–15.02)

 Physical activity

302,910

1.53

0.70 (0.66–0.75)

29.61

11.16 (9.60–12.70)

 Diet score

54,274

1.47

0.90 (0.82–0.99)

9.66

8.69 (0.71–16.03)

 Sleep pattern

134,224

1.23

0.73 (0.69–0.78)

26.90

19.71 (16.23–23.05)

 Per unit increase in healthy lifestyle score

NA

NA

0.67 (0.66–0.69)

32.86

NA

  1. T2DM Type 2 Diabetes Mellitus, HR hazard ratio, CI confidence interval, PAR% population-attributable risk percent
  2. aParticipants in the low-risk group
  3. bIncidence density per 1000 person-years
  4. cLow-risk lifestyle factors: BMI of ≤ 24.9 kg/m2; moderate alcohol consumption (0 to 15 g/day for women and 0 to 28 g/day for men). Nonsmoking; moderate to vigorous physical activity ($150 min/week), high-quality diet (top two-fifths of healthy diet score), and healthy sleep pattern (top two-fifths of healthy diet score). Adjusted for age, sex, education, socioeconomic status, parental history of T2DM or hypertension