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Table 1 Description of studies investigating the cross-sectional association of DM with AF types

From: Association of diabetes with atrial fibrillation types: a systematic review and meta-analysis

 

First author, year (Reference)

Country

N

Population

Mean age (years)

Women %

DM assessment

Adjustment for potential confounders

Outcome (Ref)

Result

1*†

Nabauer, 2009

Germany

7907

Paroxysmal, persistent, and permanent AF

68.4 ± 11.0

38.8

NR

-

Non-paroxysmal AF [i.e., persistent or permanent] (Ref: paroxysmal AF)

uOR (CI), 1.74 (1.54–1.96)

2*†

Chiang, 2012

26 countries in Europe, Asia, Africa, and South America

9816

Paroxysmal,

persistent, and permanent AF

68.3

44.2

NR

-

Non-paroxysmal AF [i.e., persistent or permanent] (Ref: paroxysmal AF)

uOR (CI), 1.20 (1.07–1.34)

3*†

Boriani, 2016

9 European countries

1815

Paroxysmal,

persistant, and permanent AF

40.15

39.8

NR

-

Non-paroxysmal AF [i.e., persistent or permanent] (Ref: paroxysmal AF)

uOR (CI), 1.40 (1.12–1.82)

4*†

Echouffo-Tcheugui, 2017

United States

6575

Paroxysmal, persistent, and permanent AF

75

42.6

Previous medical history or new DM diagnosis during enrollment visit

Non-paroxysmal AF [i.e., persistent or permanent] (Ref: paroxysmal AF)

uOR (CI), 1.18 (1.08–1.29)

5*†

Fumagalli, 2018

9 European countries

2337

Paroxysmal, persistent, long-standing persistent and permanent AF

69

40.3

NR

Non-paroxysmal AF [persistent, long-standing persistent or permanent] (Ref: paroxysmal AF)

uOR (CI), 1.46 (1.17–1.82)

6*

Ruperti 2018

Switzerland

476

Paroxysmal, persistent, and permanent AF

68

67.5

NR

Recent non-paroxysmal AF [i.e., persistent or permanent]

(Ref: paroxysmal AF)

uOR (CI), 0.94 (0.53–1.67)

Age, sex, BMI, HTN, heart rate, CAD, HF, LVH

education, history of hyperthyroidism, smoking, physical activity, alcohol

aOR (CI), 0.79 (0.40–1.54)

7*†

Schnabel, 2018

7 European countries

3210

Paroxysmal, persistent, and permanent AF

72

39.9

NR

Non-paroxysmal AF [i.e., persistent or permanent] (Ref: paroxysmal AF)

uOR (CI), 1.03 (0.87–1.21)

8*

Bhat, 2021

Australia

665

Paroxysmal, persistent, and permanent AF

66.8 ± 13.5

47

NR

Non-paroxysmal AF [i.e., persistent or permanent] (Ref: paroxysmal AF)

uOR (CI), 1.55 (1.09–2.20)

Age, HF, ischemic heart disease, anticoagulation, left ventricular ejection fraction, right atrial area, average E/e`, left atrial emptying fraction

aOR (CI), 1.42 (0.80–2.54)

  1. *The studies investigated the association of diabetes with non-paroxysmal AF (compared to paroxysmal AF)
  2. Unadjusted odds ratios for developing non-paroxysmal AF compared to paroxysmal AF were calculated manually
  3. DM diabetes mellitus, AF atrial fibrillation, NR not reported, uOR unadjusted odds ratio, BMI body mass index, HTN hypertension, CAD coronary artery disease, HF heart failure, LVH left ventricular hypertrophy, aOR adjusted odds ratio, CI 95% confidence interval, Ref reference