Association of low fasting C-peptide levels with cardiovascular risk, visit-to-visit glucose variation and severe hypoglycemia in the Veterans Affairs Diabetes Trial (VADT)

Table 2 Relationship between baseline C-peptide levels and follow-up measurements of glucose control

Outcomes were any occurrence of severe hypoglycemia, mean updated glucose coefficient of variation (CV) or average real variability (ARV). Model 1, adjusted for glucose-lowering group; Model 2, additionally adjusted for baseline age, race/ethnicity, diabetes duration, HbA_1c, body mass index and eGFR; Model 3, additionally adjusted for insulin and sulphonylureas use. Data are Odds ratios (OR) or standardized β-estimates (95% CI) per 1 SD of C-peptide levels
^†Logistic regression, ^‡Mixed model linear regression with random intercept, *p < 0.05

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