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Table 1 Baseline patient, lesion and procedural characteristics

From: Impact of prediabetes and diabetes on 3-year outcome of patients treated with new-generation drug-eluting stents in two large-scale randomized clinical trials

 

Baseline characteristics, No. (%)

Normoglycemia

n = 2353

Prediabetes

n = 489

Diabetes

n = 1488

P-value

Age, mean (SD), years

62.9 (10.8)

64.6 (10.8)

65.7 (10.6)

< 0.001

Female

568 (24.1)

142 (29.0)

439 (29.5)

< 0.001

Body mass index, mean (SD), kg/m2

26.9 (3.8)

27.9 (4.3)

29.1 (4.7)

< 0.001

Hypertension

933 (39.7)

236/488 (48.4)

948/1484 (63.9)

< 0.001

Hypercholesterolemia

909/2351 (38.7)

204/488 (41.8)

746/1479 (50.4)

< 0.001

Current smoker

764/2299 (33.2)

140/467 (30.0)

376/1440 (26.1)

< 0.001

Renal insufficiencya

55 (2.3)

21 (4.3)

114 (7.7)

< 0.001

Previous stroke

137 (5.8)

35 (7.2)

137 (9.2)

< 0.001

Previous myocardial infarction

350 (14.9)

91 (18.6)

320 (21.5)

< 0.001

Previous PCI

359 (15.3)

100 (20.4)

368 (24.7)

< 0.001

Previous CABG

140 (5.9)

40 (8.2)

156 (10.5)

< 0.001

Clinical presentation

0.001

 STEMI

763 (32.4)

146 (29.9)

379 (25.5)

 

 Non-STEMI

521 (22.1)

98 (20.0)

345 (23.2)

 

 Unstable angina

389 (16.5)

94 (19.2)

278 (18.7)

 

 Stable angina

680 (28.9)

151 (30.9)

486 (32.7)

 

Lesion and procedural characteristics

 At least 1 severely calcified lesion

450 (19.1)

108 (22.1)

344 (23.1)

0.009

 At least 1 bifurcation treated

828 (35.2)

183 (37.4)

551 (37.0)

0.41

 Graft treated

32 (1.4)

12 (2.5)

37 (2.5)

0.026

 Small vessel treated (< 2.75mm)

1256 (53.4)

282 (57.7)

910 (61.2)

< 0.001

 Multivessel treatment

398 (16.9)

100 (20.4)

275 (18.5)

0.13

 Total stent length/patient, median (IQR)

32 (20–52)

31 (20–53)

30 (18–48)

0.86

 Direct stenting

265 (15.6)

53 (14.1)

147 (16.1)

0.67

 Postdilation

1913 (81.3)

399 (81.6)

1,121(75.3)

< 0.001

 Number of diseased vessels > 50 % angiographic stenosis

   

< 0.001

  One vessel disease

1380 (58.6)

274 (56.0)

757 (50.9)

 

  Two vessel disease

737 (31.3)

158 (32.3)

487 (32.7)

 

  Three vessel disease

236 (10.0)

57 (11.7)

244 (16.4)

 
  1. Values are n/N (%), mean (SD), or median (IQR)
  2. CABG, coronary artery bypass grafting; PCI, percutaneous coronary intervention; STEMI, ST-segment-elevation myocardial infarction; NSTEMI, non-ST-segment-elevation myocardial infarction
  3. aDefined as creatinine level ≥ 130 µmol/l, an estimated glomerular filtration rate of less than 30 ml per minute per 1.73 m2 of body-surface area, or the need for dialysis
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Cardiovascular Diabetology

ISSN: 1475-2840