Fig. 2

Change in estimated glomerular filtration rate (eGFR) over time before and after index date (i.e., initiation of SGLT-2i or oGLD therapy) (on-treatment analysis): a overall study cohort, b eGFR ≤ 60 mL/min/1.73 m² subgroup, c 60 < eGFR ≤ 90 mL/min/1.73 m² subgroup, and d eGFR > 90 mL/min/1.73 m²) subgroup. oGLDs other glucose-lowering drugs, SGLT-2is sodium glucose cotransporter-2 inhibitors. Means of change in eGFR are plotted with standard error bars. The bottom tables present the number of eGFR observations available at each time point