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Table 2 Event rates and relative risks for stroke, ischaemic stroke and haemorrhagic stroke, respectively, in 104 697 people with type 2 diabetes, stratified into four groups, depending on estimated glucose disposal rate (eGDR)

From: Estimated glucose disposal rate and risk of stroke and mortality in type 2 diabetes: a nationwide cohort study

Variable eGDR (mg/kg/min) Events/person-years Rate per 1000 person-years
(95% CI)
Crude hazard ratio
(95% CI)
Age- and sex-adjusted hazard ratio (95% CI) Multivariable adjusted* hazard ratio (95% CI)
All Stroke  < 4 1106/114389 9.7 (9.1–10.3) 1.00 1.00 1.00
  4–6 1847/194940 9.5 (9.0–9.9) 0.97 (0.90–1.05) 0.78 (0.73–0.84) 0.77 (0.69–0.84)
  6–8 771/100891 7.6 (7.1–8.2) 0.79 (0.72–0.86) 0.73 (0.67–0.81) 0.68 (0.58–0.80)
   > 8 477/93028 5.1 (4.7–5.6) 0.52 (0.47–0.58) 0.59 (0.53–0.65) 0.60 (0.48–0.76)
Ischaemic stroke  < 4 912/114712 8.0 (7.4–8.5) 1.00 1.00 1.00
  4–6 1518/195541 7.8 (7.4–8.2) 0.97 (0.90–1.05) 0.78 (0.71–0.84) 0.75 (0.67–0.84)
  6–8 657/101133 6.5 (6.0–7.0) 0.81 (0.73–0.90) 0.75 (0.68–0.83) 0.68 (0.57–0.81)
   > 8 389/93197 4.2 (3.8–4.6) 0.52 (0.46–0.58) 0.58 (0.51–0.65) 0.55 (0.43–0.71)
Haemorrhagic stroke  < 4 182/116550 1.6 (1.3–1.8) 1.00 1.00 1.00
  4–6 319/198339 1.6 (1.4–1.8) 1.02 (0.85–1.22) 0.85 (0.71–1.03) 0.87 (0.69–1.10)
  6–8 114/102320 1.1 (0.9–1.3) 0.71 (0.56–0.89) 0.72 (0.57–0.91) 0.78 (0.53–1.15)
   > 8 93/93911 1.0 (0.8–1.2) 0.62 (0.48–0.80) 0.73 (0.57–0.93) 1.07 (0.61–1.88)
  1. *Multivariable adjusted (see text statistics) not adjusted for variables including in the eGDR formula, i.e. HbA1c, waist circumference and blood pressure