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Table 2 Baseline characteristics according to lower and higher TyG index in nondiabetic population stratified by gender

From: Gender difference in the association between TyG index and subclinical atherosclerosis: results from the I-Lan Longitudinal Aging Study

  Female Male
Lower TyG index; n  =  379 Higher TyG index; n  =  287 p value Lower TyG index; n  =  292 Higher TyG index; n  =  297 p value
Age (years) 60.94  ±  7.61 61.71  ±  7.64 0.198 63.29  ±  8.21 62.26  ±  8.18 0.126
BMI 23.23 (21.22–25.36) 24.79 (22.92–27.50) < 0.001 23.78 (21.97–25.85) 25.52 (23.32–27.20) < 0.001
Waist circumference 78.5 (72–85) 83 (78–90) < 0.001 84 (79–90) 88 (83–94) < 0.001
Smoking (%) 9 (2.4) 12 (4.2) 0.262 99 (33.9) 101 (34.0) 1.000
Underlying disease
 Hypertension (%) 92 (24.3) 108 (37.6) < 0.001 86 (29.5) 102 (34.3) 0.216
 Anti-hypertensive agents (%) 42 (11.1) 42 (14.6) 0.195 35 (12.0) 54 (18.2) 0.039
 CKD (%) 16 (4.2) 20 (7.0) 0.165 97 (33.4) 94 (31.6) 0.660
 Metabolic syndrome (%) 41 (10.8) 141 (49.1) < 0.001 22 (7.5) 109 (36.7) < 0.001
 Overweight (%) 110 (29.0) 136 (47.4) < 0.001 102 (34.9) 165 (55.6) < 0.001
 LDL  ≥  130 mg/dL (%) 134 (35.4) 144 (50.2) < 0.001 96 (32.9) 133 (44.8) 0.003
Laboratory data
 Total cholesterol (mg/dl) 202 (179–222) 211 (191–233) < 0.001 186 (165–209) 198 (177–218) < 0.001
 HDL (mg/dl) 64 (54–74) 53 (46–60) < 0.001 53 (46–62) 47 (40–53) < 0.001
 LDL (mg/dl) 118 (98–139) 130 (110–151) < 0.001 117 (97–137.8) 124 (101.5–143) 0.028
 Fasting glucose (mg/dl) 91 (86–96) 97 (91–105) < 0.001 92 (88–98) 96 (90.5–104) < 0.001
 HbA1c (%) 5.7 (5.5–5.9) 5.9 (5.6–6.2) < 0.001 5.7 (5.4–5.9) 5.7 (5.5–6.0) < 0.001
 Uric acid 4.9 (4.2–5.6) 5.4 (4.6–6.3) < 0.001 6.1 (5.3–6.9) 6.7 (5.9–7.7) < 0.001
 hs-CRP 0.067 (0.031–0.179) 0.101 (0.03–0.240) 0.001 0.24  ±  0.48 0.21  ±  0.36 0.361
 Triglyceride (mg/dl) 78 (60–91) 141 (124–176) < 0.001 76 (62–90) 150 (124.5–204.5) < 0.001
 eGFR (ml/min/1.73m2) 90.98 (72.30–108.23) 100.30 (79.22–114.24) 0.010 67.01  ±  18.54 70.13  ±  20.26 0.052
 Triglyceride glucose index 8.17 (7.90–8.35) 8.83 (8.67–9.07) < 0.001 8.18 (7.96–8.35) 8.88 (8.71–9.21) < 0.001
 Mean cIMT (mm) 0.64  ±  0.11 0.67  ±  0.11 0.006 0.71  ±  0.16 0.71  ±  0.14 0.698
 cIMT  ≥  0.75 mm 65 (17.2) 73 (25.4) 0.012 105 (36.0) 99 (33.3) 0.545
  1. Values are mean  ±  standard deviation or n (%)
  2. BMI body mass index, DM diabetes mellitus, CKD chronic kidney disease, HDL high density lipoprotein, LDL low density lipoprotein, HbA1c hemoglobin A1c, hs-CRP high sensitivity C-reactive protein, eGFR estimated glomerular filtration rate, cIMT carotid intima-media thickness
  3. aTriglyceride glucose index  =  ln[fasting TG (mg/dL)  ×  fasting plasma glucose (mg/dL)/2]