| |
Female
|
Male
|
|---|
|
Lower TyG index; n = 379
|
Higher TyG index; n = 287
|
p value
|
Lower TyG index; n = 292
|
Higher TyG index; n = 297
|
p value
|
|---|
|
Age (years)
|
60.94 ± 7.61
|
61.71 ± 7.64
|
0.198
|
63.29 ± 8.21
|
62.26 ± 8.18
|
0.126
|
|
BMI
|
23.23 (21.22–25.36)
|
24.79 (22.92–27.50)
|
< 0.001
|
23.78 (21.97–25.85)
|
25.52 (23.32–27.20)
|
< 0.001
|
|
Waist circumference
|
78.5 (72–85)
|
83 (78–90)
|
< 0.001
|
84 (79–90)
|
88 (83–94)
|
< 0.001
|
|
Smoking (%)
|
9 (2.4)
|
12 (4.2)
|
0.262
|
99 (33.9)
|
101 (34.0)
|
1.000
|
|
Underlying disease
|
|
Hypertension (%)
|
92 (24.3)
|
108 (37.6)
|
< 0.001
|
86 (29.5)
|
102 (34.3)
|
0.216
|
|
Anti-hypertensive agents (%)
|
42 (11.1)
|
42 (14.6)
|
0.195
|
35 (12.0)
|
54 (18.2)
|
0.039
|
|
CKD (%)
|
16 (4.2)
|
20 (7.0)
|
0.165
|
97 (33.4)
|
94 (31.6)
|
0.660
|
|
Metabolic syndrome (%)
|
41 (10.8)
|
141 (49.1)
|
< 0.001
|
22 (7.5)
|
109 (36.7)
|
< 0.001
|
|
Overweight (%)
|
110 (29.0)
|
136 (47.4)
|
< 0.001
|
102 (34.9)
|
165 (55.6)
|
< 0.001
|
|
LDL ≥ 130 mg/dL (%)
|
134 (35.4)
|
144 (50.2)
|
< 0.001
|
96 (32.9)
|
133 (44.8)
|
0.003
|
|
Laboratory data
|
|
Total cholesterol (mg/dl)
|
202 (179–222)
|
211 (191–233)
|
< 0.001
|
186 (165–209)
|
198 (177–218)
|
< 0.001
|
|
HDL (mg/dl)
|
64 (54–74)
|
53 (46–60)
|
< 0.001
|
53 (46–62)
|
47 (40–53)
|
< 0.001
|
|
LDL (mg/dl)
|
118 (98–139)
|
130 (110–151)
|
< 0.001
|
117 (97–137.8)
|
124 (101.5–143)
|
0.028
|
|
Fasting glucose (mg/dl)
|
91 (86–96)
|
97 (91–105)
|
< 0.001
|
92 (88–98)
|
96 (90.5–104)
|
< 0.001
|
|
HbA1c (%)
|
5.7 (5.5–5.9)
|
5.9 (5.6–6.2)
|
< 0.001
|
5.7 (5.4–5.9)
|
5.7 (5.5–6.0)
|
< 0.001
|
|
Uric acid
|
4.9 (4.2–5.6)
|
5.4 (4.6–6.3)
|
< 0.001
|
6.1 (5.3–6.9)
|
6.7 (5.9–7.7)
|
< 0.001
|
|
hs-CRP
|
0.067 (0.031–0.179)
|
0.101 (0.03–0.240)
|
0.001
|
0.24 ± 0.48
|
0.21 ± 0.36
|
0.361
|
|
Triglyceride (mg/dl)
|
78 (60–91)
|
141 (124–176)
|
< 0.001
|
76 (62–90)
|
150 (124.5–204.5)
|
< 0.001
|
|
eGFR (ml/min/1.73m2)
|
90.98 (72.30–108.23)
|
100.30 (79.22–114.24)
|
0.010
|
67.01 ± 18.54
|
70.13 ± 20.26
|
0.052
|
|
Triglyceride glucose index
|
8.17 (7.90–8.35)
|
8.83 (8.67–9.07)
|
< 0.001
|
8.18 (7.96–8.35)
|
8.88 (8.71–9.21)
|
< 0.001
|
|
Mean cIMT (mm)
|
0.64 ± 0.11
|
0.67 ± 0.11
|
0.006
|
0.71 ± 0.16
|
0.71 ± 0.14
|
0.698
|
|
cIMT ≥ 0.75 mm
|
65 (17.2)
|
73 (25.4)
|
0.012
|
105 (36.0)
|
99 (33.3)
|
0.545
|
- Values are mean ± standard deviation or n (%)
- BMI body mass index, DM diabetes mellitus, CKD chronic kidney disease, HDL high density lipoprotein, LDL low density lipoprotein, HbA1c hemoglobin A1c, hs-CRP high sensitivity C-reactive protein, eGFR estimated glomerular filtration rate, cIMT carotid intima-media thickness
- aTriglyceride glucose index = ln[fasting TG (mg/dL) × fasting plasma glucose (mg/dL)/2]
