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Table 1 Baseline characteristics stratified by TyG index of entire population stratified by lower and higher TyG index

From: Gender difference in the association between TyG index and subclinical atherosclerosis: results from the I-Lan Longitudinal Aging Study

 

Total cases; n  =  1457

TyG index  <  8.55; n  =  728

TyG index ≥ 8.55; n  =  729

p value

Age (years)

62.34  ±  8.00

62.31  ±  8.06

62.37  ±  7.95

0.894

Female/male (%)

767/690 (52.6/47.4)

408/320 (56.0/44.0)

359/370 (49.2/50.8)

0.010

BMI

24.81  ±  3.55

23.55 (21.66–25.79)

25.35 (23.42–27.65)

< 0.001

Waist circumference

84.28  ±  9.75

81.5 (75.0–88.0)

86.5 (80.0–93.0)

< 0.001

Smoking (%)

260 (17.8)

117 (16.1)

143 (19.6)

0.087

Underlying disease

 Hypertension (%)

520 (35.7)

212 (29.1)

308 (42.2)

< 0.001

 Anti-hypertensive agents (%)

239 (16.4)

93 (12.8)

146 (20.0)

< 0.001

 DM (%)

202 (13.9)

57 (7.8)

145 (19.9)

< 0.001

 CKD (%)

282 (19.4)

129 (17.8)

153 (21.0)

0.127

 Metabolic syndrome (%)

453 (31.1)

90 (12.4)

363 (49.8)

< 0.001

 Overweight (%)

633 (43.4)

239 (32.8)

394 (54.0)

< 0.001

 LDL  ≥  130 mg/dL (%)

554 (38.0)

239 (32.8)

315 (43.2)

< 0.001

Laboratory data

 Total cholesterol (mg/dl)

197.66  ±  35.30

193 (168–215)

202 (177–223)

< 0.001

 HDL (mg/dl)

55.16  ±  14.11

58 (50–69)

49 (42–56)

< 0.001

 LDL (mg/dl)

120.87  ±  32.57

116 (96–137)

124 (102–144)

< 0.001

 Fasting glucose (mg/dl)

101.49  ±  28.16

92 (87–98)

100 (92–111)

< 0.001

 HbA1c (%)

6.01  ±  0.98

5.7 (5.5–6.0)

5.9 (5.6–6.4)

< 0.001

 Uric acid

5.84  ±  1.50

5.4 (4.6–6.3)

6.1 (5.1–7.1)

< 0.001

 hs-CRP

0.22  ±  0.38

0.069 (0.033–0.190)

0.102 (0.041–0.245)

0.975

 Triglyceride (mg/dl)

121.85  ±  78.47

77 (60–90)

143 (123–186)

< 0.001

 eGFR (ml/min/1.73 m2)

83.33  ±  28.30

82.62  ±  27.24

84.03  ±  29.32

0.341

 Triglyceride glucose index

8.57  ±  0.58

8.18 (7.95–8.36)

8.88 (8.70–9.21)

< 0.001

 Mean cIMT (mm)

0.68  ±  0.13

0.65 (0.60–0.75)

0.70 (0.60–0.75)

0.003

 cIMT  ≥  0.75 mm (%)

417 (28.6)

189 (26.0)

228 (31.3)

0.028

  1. Values are mean  ±  standard deviation or n (%)
  2. BMI body mass index, DM diabetes mellitus, CKD chronic kidney disease, HDL high density lipoprotein, LDL low density lipoprotein, HbA1c hemoglobin A1c, hs-CRP high sensitivity C-reactive protein, eGFR estimated glomerular filtration rate, cIMT carotid intima-media thickness
  3. aTriglyceride glucose index  =  ln[fasting TG (mg/dL)  ×  fasting plasma glucose (mg/dL)/2]
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Cardiovascular Diabetology

ISSN: 1475-2840