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Table 2 Changes in cMRI measured RV parameters following treatment for 6 months with either empagliflozin or placebo

From: Impact of empagliflozin on right ventricular parameters and function among patients with type 2 diabetes

 

Empagliflozin 10 mg (n = 44)*

Placebo (n = 46)*

Baseline

6 months

Mean change (95% CI)

Baseline

6 months

Mean change (95% CI)

RV mass index, g/m2

11.5 (2.35)

11.4 (2.13)

− 0.07 (− 0.64 to 0.50)

12.8 (2.37)

11.8 (1.84)

− 0.28 (− 0.96 to 0.40)

RV end diastolic volume index, mL/m2

62.0 (13.2)

61.7 (10.8)

− 0.53 (− 3.22 to 2.16)

66.4 (12.6)

65.5 (10.4)

− 0.84 (− 3.15 to 1.47)

RV end systolic volume index, mL/m2

28.9 (6.51)

28.6 (6.24)

− 0.48 (− 1.99 to 1.03)

30.8 (6.98)

30.4 (5.60)

− 0.27 (− 1.63 to 1.08)

RV ejection fraction, %

53.2 (4.93)

53.7 (5.17)

0.53 (− 1.02 to 2.08)

53.8 (4.59)

53.5 (5.13)

− 0.35 (− 1.82 to 1.12)

  1. RV right ventricle
  2. Data expressed as percentages or mean (standard deviation) unless otherwise specified
  3. *All p-values are non-significant