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Table 4 Baseline characteristic of patients in the low and high Apo B/A1 ratio groups

From: Association between apolipoprotein B/A1 ratio and coronary plaque vulnerability in patients with atherosclerotic cardiovascular disease: an intravascular optical coherence tomography study

Characteristics

Low ratio (n = 160)

High ratio (n = 160)

P value

Male, n (%)

110 (68.8%)

139 (86.9%)

 < 0.001

Age, years, mean ± SD

61.87 ± 10.10

57.54 ± 10.38

 < 0.001

Medical history, n (%)

 Atrial fibrillation

7 (4.4%)

4 (2.5%)

0.357

 Hypertension

91 (56.9%)

75 (46.9%)

0.073

 Diabetes mellitus

51 (31.9%)

29 (18.1%)

0.005

 ASCVD

78 (48.8%)

70 (43.8%)

0.370

 Prior PCI

33 (20.6%)

32 (20.0%)

0.889

 Stroke

10 (6.3%)

9 (5.6%)

0.813

Laboratory results, mean ± SD

 HbA1c, %

6.42 ± 1.59

6.54 ± 1.80

0.530

 NT-proBNP, pg/ml

607.48 ± 1671.90

734.63 ± 2124.78

0.556

 Hs-cTnI, pg/ml

249.97 ± 1060.65

333.98 ± 890.54

0.454

 TC, mmol/L

3.28 ± 0.76

4.30 ± 0.92

 < 0.001

 TG, mmol/L

1.37 ± 0.68

2.04 ± 1.71

 < 0.001

 HDL-C, mmol/L

1.15 ± 0.27

0.96 ± 0.20

 < 0.001

 LDL-C, mmol/L

1.72 ± 0.62

2.73 ± 0.72

 < 0.001

 VLDL-C, mmol/L

0.42 ± 0.26

0.62 ± 0.60

 < 0.001

 Lipoprotein (a), mg/dl

19.56 ± 24.56

26.85 ± 31.42

0.022

 LVEF, %

63.12 ± 7.17

62.52 ± 8.40

0.529

Plaque morphology, n (%)

   

 Plaque rupture

27 (16.9)

52 (32.5%)

0.001

 Plaque erosion

12 (7.5%)

31 (19.4%)

0.002

 Calcified nodule

7 (4.4%)

5 (3.1%)

0.556

Thrombus

30 (18.8%)

59 (36.9%)

 < 0.001

 TCFA

6 (3.8%)

10 (6.3%)

0.305

 Fibrous plaque

64 (40.0%)

73 (45.6%)

0.309

  FCT, μm

955.02 ± 347.42

966.28 ± 303.87

0.844

 Calcification

56 (35.0%)

30 (18.8%)

0.001

  Angle, °

171.09 ± 122.51

208.65 ± 95.80

0.142

  Thickness, mm

0.82 ± 0.27

0.89 ± 0.33

0.310

  Length, mm

22.30 ± 11.18

24.48 ± 14.02

0.489

 Lipid-rich plaque

39 (24.4%)

40 (25.0%)

0.897

  FCT, μm

181.46 ± 154.11

114.98 ± 80.11

0.020

  Lipid arc, °

191.38 ± 72.15

186.40 ± 61.03

0.741

 Cholesterol crystal

64 (40.0%)

73 (45.6%)

0.309

 Micro-vessel

32 (20.0%)

37 (23.1%)

0.497

 Macrophage

34 (21.3%)

27 (16.9%)

0.319

Stents, n (%)

 0

56 (35.0%)

39 (24.4%)

 

 1

57 (35.6%)

67 (41.9%)

 

 2

29 (18.1%)

38 (23.8%)

 

 3

11 (6.9%)

10 (6.3%)

 

  > 3

7 (4.4%)

6 (3.8%)

 

Statins, n (%)

98 (61.3%)

110 (68.8%)

0.160

  1. ASCVD atherosclerotic cardiovascular disease, PCI percutaneous coronary intervention, SD standard deviation, HbA1c glycosylated hemoglobin, NT-proBNP N-terminal B-type natriuretic peptide, Hs-cTnI high-sensitivity cardiac troponin I, TC total cholesterol, TG total triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, VLDL-C very low-density lipoprotein cholesterol, Apo apolipoprotein, LVEF left ventricular ejection fraction, TCFA thin-cap fibroatheroma, FCT fibrous cap thickness