Skip to main content

Table 5 Stepwise regression analysis for incident diabetic patients after dialysis with 5-year survival rate, n = 335

From: Effect of anti-diabetic drugs in dialysis patients with diabetes: a nationwide retrospective cohort study

Variables

Univariate

Multivariate

HR (95% CI)

P-value

aHR (95% CI)

P-value

Age > 60 years

2.52 (1.67–3.79)

 < 0.001

2.35 (1.56–3.55)

 < 0.001

Gender—male

1.40 (0.98–2.00)

0.068

  

Anti-diabetic drug use

 OHA

1

   

 Insulin

1.63 (1.14–2.33)

0.008

1.41 (0.98–2.02)

0.068

Region

 Northern

1

   

 Central

1.23 (0.80–1.89)

0.900

  

 Southern/Eastern

0.94 (0.63–1.52)

0.398

  

Insured premium (NT$)

 < 15,840

1

   

 15,840–25,000

0.78 (0.51–1.20)

0.254

  

 > 25,000

0.87 (0.55–1.38)

0.543

  

Urbanization

 Urban

1

   

 Sub-urban

0.75 (0.50–1.12)

0.157

  

 Rural

0.84 (0.47–1.62)

0.565

  

Hospital characteristics

 Medical center

1.19 (0.81–1.76)

0.378

  

 Region/others

1

   

Number of admissions during the 12 months leading up to dialysis

 0–1

1

   

 > 1

1.59 (1.05–2.43)

0.031

  

Dialysis modality

 Peritoneal dialysis

1

   

 Hemodialysis

1.24 (0.54–2.81)

0.614

  

Comorbidity

 Hypertension

1.22 (0.85–1.75)

0.275

  

 Hyperlipidemia

0.43 (0.23–0.81)

0.008

0.45 (0.24–0.85)

0.014

 Gout

0.85 (0.50–1.46)

0.557

  

 Congestive heart failure

1.27 (0.85–1.89)

0.239

  

 Cerebrovascular accident

2.03 (1.28–3.22)

0.003

2.04 (1.27–3.29)

0.003

 COPD

1.92 (1.18–3.14)

0.009

1.68 (1.03–2.76)

0.039

 Chronic liver disease

1.00 (0.47–2.15)

0.998

  

 Malignancy

1.65 (0.98–2.80)

0.061

  

ACEI/ARB use

0.68 (0.48–0.97)

0.033

  

Lipid-lowering drugs use

0.50 (0.33–0.76)

0.001

0.66 (0.43–1.02)

0.060

  1. HR hazard ratio, CI confidence interval, aHR adjusted hazard ratio, OHA oral hypoglycemia agents, COPD chronic obstructive pulmonary disease, ACEI angiotensin converting enzyme inhibitors, ARB angiotensin II receptor blockers