Variables | Univariate | Multivariate | ||
---|---|---|---|---|
HR (95% CI) | P-value | aHR (95% CI) | P-value | |
Age > 60 year | 2.31 (2.01–2.65) | < 0.001 | 2.05 (1.78–2.35) | < 0.001 |
Gender—male | 1.09 (0.96–1.24) | 0.183 | ||
Anti-diabetic drug use | ||||
Non-user | 1 | 1 | ||
OHA | 0.44 (0.37–0.53) | < 0.001 | 0.56 (0.49–0.68) | < 0.001 |
Insulin | 0.52 (0.43–0.63) | < 0.001 | 0.66 (0.55–0.80) | < 0.001 |
Region | ||||
Northern | 1 | |||
Central | 1.01 (0.86–1.19) | 0.900 | ||
Southern/Eastern | 0.94 (0.81–1.09) | 0.398 | ||
Insured premium (NT$) | ||||
< 15,840 | 1 | |||
15,840–25,000 | 0.87 (0.75–1.02) | 0.084 | ||
> 25,000 | 0.80 (0.68–0.95) | 0.012 | ||
Urbanization | ||||
Urban | 1 | |||
Sub-urban | 1.09 (0.95–1.25) | 0.236 | ||
Rural | 1.10 (0.90–1.33) | 0.365 | ||
Hospital characteristics | ||||
Medical center | 1.03 (0.89–1.19) | 0.674 | ||
Region/others | 1 | |||
Number of admissions during the 12 months leading up to dialysis | ||||
0–1 | 1 | 1 | ||
> 1 | 1.72 (1.51–1.95) | < 0.001 | 1.59 (1.38–1.83) | < 0.001 |
Dialysis modality | ||||
Peritoneal dialysis | 1 | |||
Hemodialysis | 0.86 (0.64–1.15) | 0.306 | ||
Comorbidity | ||||
Hypertension | 1.14 (0.98–1.31) | 0.070 | 0.73 (0.67–0.91) | 0.002 |
Hyperlipidemia | 0.80 (0.69–0.93) | 0.003 | ||
Gout | 1.07 (0.86–1.32) | 0.562 | ||
Congestive heart failure | 1.22 (1.07–1.39) | 0.003 | ||
Cerebrovascular accident | 1.35 (1.16–1.57) | < 0.001 | 1.21 (1.03–1.41) | 0.020 |
COPD | 1.57 (1.27–1.64) | < 0.001 | 1.21 (0.98–1.49) | 0.087 |
Chronic liver disease | 1.65 (1.32–2.07) | < 0.001 | 1.48 (1.18–1.86) | 0.001 |
Malignancy | 1.65 (1.36–2.01) | < 0.001 | 1.24 (1.01–1.52) | 0.037 |
ACEI/ARB use | 0.59 (0.52–0.67) | < 0.001 | 0.56 (0.47–0.68) | < 0.001 |
Lipid-lowering drug use | 0.50 (0.43–0.58) | < 0.001 | 0.66 (0.55–0.80) | < 0.001 |