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Table 3 Unadjusted and adjusted hazard ratio of the association of sex with cardiovascular mortalitya stratified by type 2 diabetes mellitus status (n = 7443)

From: Association of sex-specific differences in lipoprotein(a) concentrations with cardiovascular mortality in individuals with type 2 diabetes mellitus

  No type 2 diabetes mellitus (n = 6988) Type 2 diabetes mellitus (n = 455)
Hazard ratio (95%-CI) p-value Hazard ratio (95%-CI) p-value
Model 1
 Men versus women 1.88 (1.58; 2.24) < 0.001 1.28 (0.89; 1.83) 0.178
Model 2
 Men versus women 1.84 (1.54; 2.20) < 0.001 1.36 (0.94; 1.97) 0.107
 Age (years) 1.15 (1.14; 1.17) < 0.001 1.12 (1.09; 1.15) < 0.001
 Body mass index (kg/m2) 1.06 (1.04; 1.08) < 0.001 1.00 (0.96; 1.04) 0.934
 Low-density lipoprotein cholesterol (mmol/L) 1.02 (0.94; 1.12) 0.599 1.05 (0.86; 1.28) 0.623
 Fasting status 1.23 (0.83; 1.81) 0.306 1.50 (0.45; 4.98) 0.503
 Hypertension 1.59 (1.28; 1.97) < 0.001 1.59 (0.92; 2.76) 0.097
 Smoking 2.10 (1.66; 2.65) < 0.001 2.21 (1.31; 3.73) 0.003
Model 3
 Men versus women 1.84 (1.54; 2.20) < 0.001 1.48 (1.01; 2.18) 0.034
 Age (years) 1.15 (1.14; 1.17) < 0.001 1.12 (1.09; 1.16) < 0.001
 Body mass index (kg/m2) 1.06 (1.04; 1.08) < 0.001 1.01 (0.96; 1.05) 0.782
 Low-density lipoprotein cholesterol (mmol/L) 1.02 (0.93; 1.11) 0.697 1.04 (0.85; 1.27) 0.691
 Fasting status 1.22 (0.83; 1.80) 0.318 1.61 (0.49; 5.33) 0.433
 Hypertension 1.59 (1.28; 1.98) < 0.001 1.62 (0.94; 2.81) 0.083
 Smoking 2.10 (1.66; 2.65) < 0.001 2.28 (1.35; 3.84) 0.002
 Lipoprotein(a) (100 mg/L) 1.01 (0.98; 1.05) 0.482 1.07 (1.02; 1.13) 0.006
  1. Data are reported as Hazard Ratios (95% confidence intervals [CI]) and p-values derived from Cox regression models. All models (including model 1) were also adjusted for study sample
  2. aCardiovascular mortality = ICD-10 codes: I10 to I79 and R99 in SHIP-0 and I10 to I99 in MONICA/KORA S3