Fig. 1

Network of protein biomarkers which were significant differentially detected in patients with diabetes compared to non-diabetics. Knowledge-based induced network with the plasma protein biomarkers which were significantly increased or decreased in diabetic patients (FDRq < 0.05) and their intermediates. The full names of biomarkers are depicted in Additional file 1: Table S1. Additionally, 1 collagen metabolism plasma biomarker (PICP) is also included in this network