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Table 4 Univariable and multivariable analysis between the magnitude of LV peak strain and clinical indices in T2DM with FMR patients

From: Aggravation of functional mitral regurgitation on left ventricle stiffness in type 2 diabetes mellitus patients evaluated by CMR tissue tracking

 

Radial PS

Circumferential PS

Longitudinal PS

Univariate

Multivariate

Univariate

Multivariate

Univariate

Multivariate

R

β (R2 = 0.185)

P

95% CI

R

β (R2 = 0.211)

P

95% CI

R

β (R2 = 0.271)

P

95% CI

Regurgitation degree

− 0.304a

− 0.272

0.029

− 6.043 to − 0.337

− 0.385a

− 0.412

0.001

− 3.975 to − 1.067

− 0.399a

− 0.347

0.004

− 2.393 to − 0.484

Months with diabetes

− 0.301a

− 0.299

0.017

− 0.975 to − 0.100

− 0.235

N/A

N/A

N/A

− 0.373a

− 0.347

0.004

− 0.366 to − 0.074

Fasting plasma glucose

0.091a

0.130

0.307

N/A

0.145

N/A

N/A

N/A

0.145

N/A

N/A

N/A

HbA1c

− 0.124

N/A

N/A

N/A

− 0.125

N/A

N/A

N/A

− 0.125

N/A

N/A

N/A

TC

0.126

N/A

N/A

N/A

0.089a

0.203

0.086

N/A

0.089a

0.094

0.437

N/A

TG

0.201

N/A

N/A

N/A

0.205

N/A

N/A

N/A

0.205

N/A

N/A

N/A

HDL

0.164

N/A

N/A

N/A

0.182

N/A

N/A

N/A

0.182

N/A

N/A

N/A

LDL

− 0.051a

0.143

0.266

N/A

− 0.097a

0.152

0.216

N/A

− 0.097a

0.959

0.628

N/A

  1. a, P < 0.1 were included in the stepwise multiple linear regression model. Adjusted by gender, sex, age, BMI, systolic blood pressure, and rest heart rate
  2. PS peak strain, HbA1c glycated haemoglobin, TC total cholesterol, TG triglycerides, HDL high-density lipoprotein, LDL low-density lipoprotein, CI confidence intervals