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Table 2 Comparison of CMR findings among T2DM patients with/without FMR and normal controls

From: Aggravation of functional mitral regurgitation on left ventricle stiffness in type 2 diabetes mellitus patients evaluated by CMR tissue tracking

 

Normal (n = 52)

T2DM

 

Without FMR

(n = 98)

With FMR (n = 59)

LV function parameters

   

 LVEDV, ml

121.1 ± 27.1

125.6 (104.3, 158.4)

172.6 (127.1, 261.3)*†

 LVESV, ml

42.7 (37.2, 49.6)

45.6 (35.1, 62.2)

93.2 (52.6, 176.7)*†

 LVSV, ml

76.4 ± 18.5

77.4 ± 23.5

75.0 (62.6, 85.9)

 LVEF, %

62.6 ± 5.8

61.9 (57.0, 66.8)

42.2 (30.3, 60.3)*†

 LV mass, g

72.1 ± 19.1

91.2 (70.4,115.0)*

111.3 ± 40.9*†

PS, %

   

 Radial

38.4 ± 8.7

31.3 ± 9.8*

18.3 ± 9.7*†

 Circumferential

− 19.9 ± 2.7

− 19.6 (− 22.2, − 16.9)

− 11.8 ± 5.1*†

 Longitudinal

− 14.8 ± 3.3

− 13.3 ± 3.2*

− 9.3 ± 3.4*†

PSSR, 1/s

   

 Radial

2.1 ± 0.7

1.7 (1.4, 2.1)*

1.0 (0.6, 1.5)*†

 Circumferential

− 1.0 (− 1.1, − 0.9)

− 1.0 (− 1.2, − 0.8)

− 0.7 ± 0.3*†

 Longitudinal

− 0.8 (− 0.9, − 0.6)

− 0.8 (− 0.9, − 0.6)

− 0.5 (− 0.7, − 0.4)*†

PDSR, 1/s

   

 Radial

− 2.8 ± 0.9

− 1.9 (− 2.4, − 1.3)*

− 1.2 (− 1.7, − 0.6)*†

 Circumferential

1.2 ± 0.3

1.1 ± 0.3*

0.7 ± 0.3*†

 Longitudinal

0.9 (0.8, 1.2)

0.8 (0.6, 1.1)

0.6 ± 0.2*†

  1. *P < 0.05, T2DM vs. Normal; †P < 0.05, T2DM patients with FMR vs. T2DM patients without FMR. T2DM type 2 diabetes mellitus, FMR functional mitral regurgitation, LV left ventricular, EDV end diastolic volume, ESV end systolic volume, SV stroke volume, EF ejection fraction, PS peak strain, PSSR peak systolic strain rate, PDSR peak diastolic strain rate