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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Comparison of the clinical effect of empagliflozin on glycemic and non-glycemic parameters in Japanese patients with type 2 diabetes and cardiovascular disease treated with or without baseline metformin

Fig. 1

Change in clinical parameters from baseline to week 24 in patients treated with empagliflozin according to baseline use of metformin. Blue (red) indicates the group with (without) baseline metformin therapy. Values located at the bottom of each panel indicate the mean group difference (95% confidence interval) in the magnitude of change from baseline to week 24 in systolic blood pressure (A), diastolic blood pressure (B), heart rate (C), double product (systolic blood pressure × heart rate: D body mass index (E), fasting plasma glucose (F), glycohemoglobin (G), and glycoalbumin (H) or the mean group ratio (95% confidence interval) of the change ratio from baseline to 24 weeks in the geometric means of NT-proBNP (I) and hs-TnI (J). hs-TnI, high-sensitivity Troponin-I; NT-proBNP, N-terminal pro-brain natriuretic peptide

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