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Table 3 Baseline parameters predictive of new-onset diabetes over 4.6 years, examined using multiple logistic regression (n = 4797)

From: FGF21/adiponectin ratio predicts deterioration in glycemia: a 4.6-year prospective study in China

 

Model 1

Model 2

Model 3

 

A

B

C

A

B

C

A

B

C

Age

1.04 (0.89–1.21)

1.02 (0.88–1.19)

1.03 (0.88–1.19)

1.05 (0.90–1.22)

1.03 (0.88–1.20)

1.03 (0.89–1.20)

1.03 (0.88–1.20)

1.01 (0.87–1.18)

1.01 (0.87–1.18)

BMI

1.25 (0.98–1.59)

1.25 (0.98–1.59)

1.25 (0.99–1.59)

1.05 (0.82–1.33)

1.05 (0.82–1.33)

1.05 (0.83–1.32)

1.01 (0.79–1.29)

1.00 (0.79–1.28)

1.02 (0.81–1.29)

Waist circumference

1.01 (0.78–1.30)

1.01 (0.79–1.31)

1.04 (0.81–1.33)

1.08 (0.84–1.39)

1.08 (0.84–1.39)

1.10 (0.87–1.40)

1.05 (0.82–1.35)

1.06 (0.82–1.36)

1.06 (0.83–1.35)

SBP

1.17 (1.00–1.36)

1.16 (1.00–1.36)

1.18 (1.02–1.37)

1.23 (1.06–1.43)

1.23 (1.06–1.42)

1.25 (1.08–1.44)

1.27 (1.09–1.47)

1.26 (1.08–1.47)

1.28 (1.10–1.48)

Triglyceridea

0.81 (0.66–0.99)

0.82 (0.67–1.00)

0.89 (0.74–1.08)

0.79 (0.64–0.96)

0.79 (0.64–0.97)

0.88 (0.72–1.06)

0.82 (0.66–1.01)

0.82 (0.67–1.01)

0.91 (0.75–1.10)

HDL-Ca

0.66 (0.53–0.82)

0.63 (0.51–0.78)

0.67 (0.54–0.83)

0.79 (0.63–0.98)

0.76 (0.61–0.94)

0.79 (0.64–0.97)

0.78 (0.62–0.97)

0.75 (0.60–0.93)

0.79 (0.63–0.98)

LDL-C

1.14 (0.96–1.35)

1.14 (0.96–1.35)

1.09 (0.93–1.29)

1.05 (0.89–1.25)

1.06 (0.89–1.25)

1.02 (0.87–1.20)

0.95 (0.80–1.13)

0.96 (0.81–1.14)

0.92 (0.78–1.08)

hsCRPa

1.20 (1.02–1.41)

1.21 (1.03–1.42)

1.22 (1.05–1.43)

1.14 (0.97–1.33)

1.15 (0.98–1.34)

1.16 (1.00–1.35)

1.11 (0.94–1.32)

1.12 (0.95–1.32)

1.14 (0.97–1.34)

Sex

1.06 (0.75–1.50)

0.97 (0.68–1.37)

1.30 (0.91–1.85)

0.71 (0.51–1.00)

0.65 (0.46–0.91)

0.81 (0.58–1.15)

0.67 (0.47–0.95)

0.61 (0.43–0.87)

0.77 (0.54–1.09)

HOMA-IRa

0.89 (0.72–1.10)

0.92 (0.74–1.14)

0.85 (0.69–1.04)

1.23 (1.01–1.49)

1.27 (1.05–1.54)

1.22 (1.00–1.48)

1.20 (0.98–1.47)

1.24 (1.01–1.52)

1.18 (0.97–1.45)

FPG

2.67 (2.23–3.20)

2.67 (2.23–3.19)

2.76 (2.32–3.29)

      

2hPG

   

1.79 (1.52–2.12)

1.81 (1.53–2.14)

1.75 (1.49–2.05)

   

HbA1c

      

3.45 (2.82–4.21)

3.46 (2.84–4.23)

3.47 (2.87–4.21)

FGF21/adiponectin ratioa

1.45 (1.21–1.74)

  

1.42 (1.19–1.69)

  

1.36 (1.13–1.63)

  

FGF21a

 

1.36 (1.15–1.61)

  

1.37 (1.15–1.62)

  

1.31 (1.10–1.56)

 

Adiponectina

  

0.80 (0.67–0.96)

  

0.87 (0.73–1.03)

  

0.87 (0.73–1.04)

  1. Data are presented as OR (95% CI). ORs were estimated as per SD increase
  2. 2hPG: 2-h plasma glucose; BMI: body mass index; FGF21: fibroblast growth factor 21; FPG: fasting plasma glucose; HDL-C: high-density lipoprotein cholesterol; HOMA-IR: homeostasis model assessment of insulin resistance; hsCRP: high-sensitivity C-reactive protein; LDL-C: low-density lipoprotein cholesterol; SBP: systolic blood pressure
  3. aLoge-transformed before analysis
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Cardiovascular Diabetology

ISSN: 1475-2840