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Table 2 Baseline characteristics of subjects with or without new-onset diabetes at 4.6 years (n = 4797)

From: FGF21/adiponectin ratio predicts deterioration in glycemia: a 4.6-year prospective study in China

  Without new-onset diabetes With new-onset diabetes p value
n 4602 195  
Males (%) 43.79 47.18 0.350
Age (years) 61.65 ± 3.97 62.01 ± 3.96 0.212
Current smoker (%) 21.84 27.69 0.054
Current Drinker (%) 15.49 13.33 0.413
BMI (kg/m2) 24.56 ± 3.17 26.02 ± 3.25 < 0.001
Waist circumference (cm) 83.98 ± 9.25 87.96 ± 8.52 < 0.001
Systolic blood pressure (mmHg) 134.26 ± 16.13 140.38 ± 17.38 < 0.001
Diastolic blood pressure (mmHg) 83.99 ± 8.66 86.22 ± 8.74 < 0.001
Total cholesterol (mmol/L) 5.20 ± 0.97 5.24 ± 1.02 0.582
Triglyceride (mmol/L)a 1.26 (0.89,1.84) 1.55 (1.04,2.11) < 0.001
HDL-C (mmol/L)a 1.32 (1.09,1.56) 1.22 (0.99,1.40) < 0.001
LDL-C (mmol/L) 3.13 ± 0.79 3.19 ± 0.84 0.237
hsCRP (μg/mL)a 0.80 (0.42,1.61) 1.19 (0.73,2.26) < 0.001
Fasting plasma glucose (mmol/L) 5.74 ± 0.49 6.20 ± 0.46 < 0.001
2-h plasma glucose (mmol/L) 7.25 ± 1.69 8.36 ± 1.69 < 0.001
Prediabetes (%) 66.56 92.82 < 0.001
Fasting insulin (μU/mL)a 6.38 (4.58,8.97) 7.91 (5.51,11.27) < 0.001
HOMA-β (%)a 57.81 (40.99,81.52) 60.28 (39.60,84.53) 0.802
HOMA-IRa 1.63 (1.14,2.33) 2.16 (1.48,3.22) < 0.001
HbA1c (mmol/mol) 37.28 ± 3.85 41.43 ± 3.97 < 0.001
HbA1c (%) 5.56 ± 0.35 5.94 ± 0.36 < 0.001
FGF21 (pg/mL)a 223.98 (135.62,342.64) 304.08 (183.70,493.50) < 0.001
Adiponectin (μg/mL)a 4.21 (3.20,5.63) 3.50 (2.60,4.65) < 0.001
FGF21/adiponectin ratio (pg/μg)a 52.78 (28.77,91.88) 85.49 (41.72,166.18) < 0.001
  1. Data are presented as mean ± SD or median (interquartile range)
  2. BMI: body mass index; FGF21: fibroblast growth factor 21; HDL-C: high-density lipoprotein cholesterol; HOMA: homeostasis model assessment; hsCRP: high-sensitivity C-reactive protein; IR: insulin resistance; LDL-C: low-density lipoprotein cholesterol
  3. aLoge-transformed before analysis