Skip to main content

Table 2 Baseline characteristics of subjects with or without new-onset diabetes at 4.6 years (n = 4797)

From: FGF21/adiponectin ratio predicts deterioration in glycemia: a 4.6-year prospective study in China

 

Without new-onset diabetes

With new-onset diabetes

p value

n

4602

195

 

Males (%)

43.79

47.18

0.350

Age (years)

61.65 ± 3.97

62.01 ± 3.96

0.212

Current smoker (%)

21.84

27.69

0.054

Current Drinker (%)

15.49

13.33

0.413

BMI (kg/m2)

24.56 ± 3.17

26.02 ± 3.25

< 0.001

Waist circumference (cm)

83.98 ± 9.25

87.96 ± 8.52

< 0.001

Systolic blood pressure (mmHg)

134.26 ± 16.13

140.38 ± 17.38

< 0.001

Diastolic blood pressure (mmHg)

83.99 ± 8.66

86.22 ± 8.74

< 0.001

Total cholesterol (mmol/L)

5.20 ± 0.97

5.24 ± 1.02

0.582

Triglyceride (mmol/L)a

1.26 (0.89,1.84)

1.55 (1.04,2.11)

< 0.001

HDL-C (mmol/L)a

1.32 (1.09,1.56)

1.22 (0.99,1.40)

< 0.001

LDL-C (mmol/L)

3.13 ± 0.79

3.19 ± 0.84

0.237

hsCRP (μg/mL)a

0.80 (0.42,1.61)

1.19 (0.73,2.26)

< 0.001

Fasting plasma glucose (mmol/L)

5.74 ± 0.49

6.20 ± 0.46

< 0.001

2-h plasma glucose (mmol/L)

7.25 ± 1.69

8.36 ± 1.69

< 0.001

Prediabetes (%)

66.56

92.82

< 0.001

Fasting insulin (μU/mL)a

6.38 (4.58,8.97)

7.91 (5.51,11.27)

< 0.001

HOMA-β (%)a

57.81 (40.99,81.52)

60.28 (39.60,84.53)

0.802

HOMA-IRa

1.63 (1.14,2.33)

2.16 (1.48,3.22)

< 0.001

HbA1c (mmol/mol)

37.28 ± 3.85

41.43 ± 3.97

< 0.001

HbA1c (%)

5.56 ± 0.35

5.94 ± 0.36

< 0.001

FGF21 (pg/mL)a

223.98 (135.62,342.64)

304.08 (183.70,493.50)

< 0.001

Adiponectin (μg/mL)a

4.21 (3.20,5.63)

3.50 (2.60,4.65)

< 0.001

FGF21/adiponectin ratio (pg/μg)a

52.78 (28.77,91.88)

85.49 (41.72,166.18)

< 0.001

  1. Data are presented as mean ± SD or median (interquartile range)
  2. BMI: body mass index; FGF21: fibroblast growth factor 21; HDL-C: high-density lipoprotein cholesterol; HOMA: homeostasis model assessment; hsCRP: high-sensitivity C-reactive protein; IR: insulin resistance; LDL-C: low-density lipoprotein cholesterol
  3. aLoge-transformed before analysis