From: FGF21/adiponectin ratio predicts deterioration in glycemia: a 4.6-year prospective study in China
 | Without new-onset diabetes | With new-onset diabetes | p value |
---|---|---|---|
n | 4602 | 195 | Â |
Males (%) | 43.79 | 47.18 | 0.350 |
Age (years) | 61.65 ± 3.97 | 62.01 ± 3.96 | 0.212 |
Current smoker (%) | 21.84 | 27.69 | 0.054 |
Current Drinker (%) | 15.49 | 13.33 | 0.413 |
BMI (kg/m2) | 24.56 ± 3.17 | 26.02 ± 3.25 | < 0.001 |
Waist circumference (cm) | 83.98 ± 9.25 | 87.96 ± 8.52 | < 0.001 |
Systolic blood pressure (mmHg) | 134.26 ± 16.13 | 140.38 ± 17.38 | < 0.001 |
Diastolic blood pressure (mmHg) | 83.99 ± 8.66 | 86.22 ± 8.74 | < 0.001 |
Total cholesterol (mmol/L) | 5.20 ± 0.97 | 5.24 ± 1.02 | 0.582 |
Triglyceride (mmol/L)a | 1.26 (0.89,1.84) | 1.55 (1.04,2.11) | < 0.001 |
HDL-C (mmol/L)a | 1.32 (1.09,1.56) | 1.22 (0.99,1.40) | < 0.001 |
LDL-C (mmol/L) | 3.13 ± 0.79 | 3.19 ± 0.84 | 0.237 |
hsCRP (μg/mL)a | 0.80 (0.42,1.61) | 1.19 (0.73,2.26) | < 0.001 |
Fasting plasma glucose (mmol/L) | 5.74 ± 0.49 | 6.20 ± 0.46 | < 0.001 |
2-h plasma glucose (mmol/L) | 7.25 ± 1.69 | 8.36 ± 1.69 | < 0.001 |
Prediabetes (%) | 66.56 | 92.82 | < 0.001 |
Fasting insulin (μU/mL)a | 6.38 (4.58,8.97) | 7.91 (5.51,11.27) | < 0.001 |
HOMA-β (%)a | 57.81 (40.99,81.52) | 60.28 (39.60,84.53) | 0.802 |
HOMA-IRa | 1.63 (1.14,2.33) | 2.16 (1.48,3.22) | < 0.001 |
HbA1c (mmol/mol) | 37.28 ± 3.85 | 41.43 ± 3.97 | < 0.001 |
HbA1c (%) | 5.56 ± 0.35 | 5.94 ± 0.36 | < 0.001 |
FGF21 (pg/mL)a | 223.98 (135.62,342.64) | 304.08 (183.70,493.50) | < 0.001 |
Adiponectin (μg/mL)a | 4.21 (3.20,5.63) | 3.50 (2.60,4.65) | < 0.001 |
FGF21/adiponectin ratio (pg/μg)a | 52.78 (28.77,91.88) | 85.49 (41.72,166.18) | < 0.001 |