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Fig. 6 | Cardiovascular Diabetology

Fig. 6

From: The SGLT-2 inhibitor empagliflozin improves myocardial strain, reduces cardiac fibrosis and pro-inflammatory cytokines in non-diabetic mice treated with doxorubicin

Fig. 6

Cardiac function studies in mice treated with saline solution (Sham), EMPA 10 mg/kg/day, DOXO 2.17 mg/kg/day or EMPA plus DOXO (n = 6 for each group). Cardiac function parameters IVS;d-D (mm), LVID;d-D (mm), LVID;s-D (mm), LVPW;d-D (mm), EF (%), FS (%), LV Mass (mg), LV Vol; d (µl), LV Vol; s (µl) were determined through non-invasive transthoracic echocardiography Vevo 2100. (two-way ANOVA with a Bonferroni post hoc test). Values are expressed ± SD. *** P < 0.001; **P < 0.01; * P < 0.05; ns: not significant

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