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Table 3 The impact of central (WHtR) versus general obesity (BMI) on the risk of heart failure hospitalization or death in different stages of diabetic nephropathy

From: The impact of central obesity on the risk of hospitalization or death due to heart failure in type 1 diabetes: a 16-year cohort study

 

Normoalbuminuria

Microalbuminuria

Macroalbuminuria

HR (95% CI)

n (%)

3324 (71.2)

644 (13.8)

700 (15.0)

 WHtR (per 0.1)

1.21 (0.86–1.70)

2.33 (1.48–3.67)

1.64 (1.26–2.13)

 WHtR (per 1 SD)

1.08 (0.87–1.35)

1.72 (1.29–2.29)

1.37 (1.16–1.62)

 BMI (per 1 kg/m2)

1.01 (0.95–1.07)

1.07 (0.99–1.15)

1.07 (1.03–1.12)

 BMI (per 1 SD)

0.99 (0.78–1.25)

1.29 (0.97–1.71)

1.28 (1.08–1.52)

  1. Multivariable Cox-regression model was adjusted for sex, age at onset of diabetes, duration of diabetes, glycated hemoglobin A1c, systolic blood pressure, HDL-cholesterol, triglycerides, history of smoking, lipid-lowering, antihypertensive and antidepressant medications, and estimated glomerular filtration rate
  2. HR hazard ratio; CI confidence interval; SD standard deviation; WHtR waist-height ratio; BMI body mass index