1. No-diabetes w/o event | 2. No-diabetes with event | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
NHIS | NHIS + Eze | HIS | HIS + Eze | p value* | NHIS | NHIS + Eze | HIS | HIS + Eze | p value* | |
Nr. patients | 16,131 (85) | 1305 (7) | 1492 (8) | 123 (1) | 3946 (47) | 738 (9) | 3265 (39) | 374 (5) | ||
Adherent | 12,586 (78) | 1091 (84) | 1213 (81) | 112 (91) | < 0.001 | 3186 (81) | 660 (89) | 2767 (85) | 356 (95) | < 0.001 |
Total-chol (mg/dl)a | 180.3 (37) | 178.5 (43) | 168.7 (43) | 170.1 (46) | < 0.001 | 152.6 (39) | 150.2 (36) | 139.1 (33) | 136.6 (33) | < 0.001 |
LDL-chol (mg/dl)a | 103.8 (31) | 100.8 (36) | 95.6 (36) | 100 (42) | < 0.001 | 84.5 (31) | 79.5 (28) | 75.4 (27) | 72.7 (26) | < 0.001 |
HDL-chol (mg/dl)a | 56.2 (16) | 55.6 (15) | 52.7 (16) | 52.5 (14) | < 0.001 | 49 (16) | 50.6 (15) | 46.5 (14) | 47.2 (13) | < 0.001 |
Triglycerides (mg/dl)a | 97.6 (58) | 102.9 (65) | 97.2 (66) | 85.1 (47) | 0.001 | 86.4 (59) | 92.4 (65) | 78.7 (54) | 74 (48) | < 0.001 |
NON-HDL-chol (mg/dl)a | 124.1 (34) | 122.8 (42) | 116 (40) | 117.6 (45) | < 0.001 | 103.6 (35) | 99.6 (33) | 92.6 (30) | 89.4 (31) | < 0.001 |
GFR (ml/min/1.73 m2)a | 91.8 (26) | 89.6 (25) | 95.2 (31) | 93.4 (44) | < 0.001 | 80.4 (34) | 80.3 (30) | 89.6 (30) | 92.3 (23) | < 0.001 |
HbA1c (mmol/mol)a | 41 (8) | 40.8 (6) | 41.3 (7) | 40.7 (6) | N.S | 40 (7) | 39.7 (5) | 39.6 (6) | 40.6 (8) | N.S |
CHD | 1672 (42) | 398 (54) | 1197 (37) | 215 (58) | < 0.001 | |||||
Cerebrovascular disease | 1565 (40) | 171 (23) | 1307 (40) | 44 (12) | < 0.001 | |||||
PAD | 4 (0) | N.I | N.I | 0 (0) | N.S | |||||
ACEi/ARB | 9001 (56) | 710 (54) | 906 (61) | 77 (63) | 0.001 | 2608 (66) | 520 (71) | 2269 (70) | 278 (74) | < 0.001 |
Beta blockers | 4178 (26) | 359 (28) | 539 (36) | 51 (42) | < 0.001 | 2041 (52) | 491 (67) | 1914 (59) | 277 (74) | < 0.001 |
CCB | 3183 (20) | 248 (19) | 296 (20) | 16 (13) | N.S | 1096 (28) | 183 (25) | 782 (24) | 72 (19) | < 0.001 |
Fibrates | 83 (1) | 7 (1) | 12 (1) | N.I | N.S | 16 (0) | 7 (1) | 9 (0) | N.I | N.S |