Characteristic | Mortality | ICU Admission | Mechanical ventilation | |||
---|---|---|---|---|---|---|
OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | |
Total cohort | ||||||
 Unadjusted | 0.76 (0.55–1.05) | 0.1 | 0.70 (0.51–0.95) | 0.02 | 0.64 (0.45–0.90) | 0.01 |
 Fully adjusted* | 0.61 (0.42–0.90) | 0.01 | 0.61 (0.43–0.87) | 0.006 | 0.54 (0.36–0.80) | 0.002 |
 Optimal Model | 0.64 (0.45–0.91)†| 0.01 | 0.64 (0.46–0.89)‡ | 0.008 | 0.56 (0.39–0.82)§ | 0.002 |
 PS matched cohort | 0.47 (0.32–0.70) |  < 0.001 | 0.55 (0.37–0.80) | 0.002 | 0.51 (0.34–0.78) | 0.002 |
 PS matched cohort, double robust approach# | 0.44 (0.30–0.66) |  < 0.001 | 0.54 (0.37–0.80) | 0.002 | 0.51 (0.33–0.77) | 0.001 |
Diabetes mellitus patients | ||||||
 Unadjusted | 0.45 (0.29–0.71) |  < 0.001 | 0.58 (0.38–0.89) | 0.01 | 0.44 (0.28–0.70) |  < 0.001 |
 Fully adjusted** | 0.35 (0.21–0.61) |  < 0.001 | 0.56 (0.34–0.90) | 0.02 | 0.39 (0.23–0.65) |  < 0.001 |
 Optimal Model | 0.37 (0.23–0.62)††|  < 0.001 | 0.58 (0.37–0.90)‡‡ | 0.02 | 0.44 (0.27–0.72)§§ |  < 0.001 |
 PS matched- Diabetes | 0.39 (0.23–0.66) |  < 0.001 | 0.58 (0.35–0.96) | 0.03 | 0.44 (0.26–0.75) | 0.003 |
Non-diabetes mellitus patients | ||||||
 Unadjusted | 1.21 (0.77–1.91) | 0.42 | 0.72 (0.45–1.15) | 0.17 | 0.81 (0.47–1.39) | 0.45 |
 Fully adjusted** | 1.21 (0.67–2.17) | 0.52 | 0.71 (0.41–1.25) | 0.23 | 0.92 (0.49–1.74) | 0.79 |
 PS matched- non-Diabetes | 0.95 (0.52–1.75) | 0.88 | 0.61 (0.33–1.14) | 0.12 | 0.82 (0.40–1.68) | 0.58 |
Cohort of patients with history of antecedent statin use | ||||||
 Unadjusted | 0.56 (0.37–0.85) | 0.006 | 0.48 (0.33–0.72) |  < 0.001 | 0.44 (0.29–0.68) |  < 0.001 |
 Fully adjusted* | 0.46 (0.28–0.74) | 0.002 | 0.46 (0.30–0.72) |  < 0.001 | 0.40 (0.25–0.65) |  < 0.001 |