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Table 2 Baseline characteristics for patients with different glycemic metabolism status

From: Prognostic value of fibrinogen in patients with coronary artery disease and prediabetes or diabetes following percutaneous coronary intervention: 5-year findings from a large cohort study

Variables Total (n = 6140) NG (n = 1394) Pre-DM (n = 2884) DM (n = 1862) P value
Age, years 58.4 ± 10.4 55.9 ± 10.8 58.9 ± 10.4 59.4 ± 9.8  < 0.001
Male, % 4771 (77.7) 1138(81.6) 2224(77.1) 1409(75.7)  < 0.001
BMI, kg/m2 25.9 ± 3.2 25.7 ± 3.1 25.8 ± 3.2 26.2 ± 3.2  < 0.001
Hypertension, % 3930 (64.0) 830(59.5) 1791(62.1) 1309(70.3)  < 0.001
Dyslipidemia, % 4241 (69.1) 906(65.0) 1910(66.2) 1425(76.5)  < 0.001
Family history of CAD, % 1433 (23.3) 355(25.5) 653(22.6) 425(22.8) 0.101
Smoking, % 3496 (56.9) 810(58.1) 1664(57.7) 1022(54.9) 0.098
Prior MI, % 1219 (19.9) 265(19.0) 567(19.7) 387(20.8) 0.426
Prior PCI or CABG, % 1581 (25.7) 322(23.1) 729(25.3) 530(28.5) 0.002
Prior stroke, % 658 (10.7) 130(9.3) 279(9.7) 249(13.4)  < 0.001
Clinical presentation, %  < 0.001
 SAP 2572 (41.9) 537 (38.5) 1193 (41.4) 842 (45.2)  
 ACS 3568 (58.1) 857 (61.5) 1691 (58.6) 1020 (54.8)  
 LVEF, % 63.0 ± 7.2 63.0 ± 7.2 63.3 ± 7.1 62.6 ± 7.4  < 0.001
 FBG, mmol/L 6.1 ± 2.0 4.7 ± 0.4 5.2 ± 0.6 7.3 ± 2.5 0.009
 HbA1c, % 6.6 ± 1.2 5.4 ± 0.2 6.0 ± 0.2 7.5 ± 1.3  < 0.001
 FIB, mg/dL 3.40 ± 0.84 3.32 ± 0.85 3.39 ± 0.85 3.47 ± 0.82  < 0.001
 hs-CRP, mg/L 3.14 ± 3.77 3.06 ± 3.82 3.11 ± 3.71 3.26 ± 3.82 0.260
 D-dimer, μg/mL 0.41 ± 0.65 0.38 ± 0.50 0.42 ± 0.65 0.42 ± 0.73 0.376
 TC, mmol/L 4.17 ± 1.09 4.18 ± 1.10 4.21 ± 1.08 4.10 ± 1.10 0.004
 HDL-C, mmol/L 1.02 ± 0.28 1.01 ± 0.28 1.04 ± 0.28 0.99 ± 0.27  < 0.001
 LDL-C, mmol/L 2.48 ± 0.92 2.50 ± 0.94 2.51 ± 0.92 2.41 ± 0.90 0.001
 TG, mmol/L 1.81 ± 1.12 1.78 ± 1.09 1.75 ± 0.94 1.92 ± 1.37  < 0.001
 Creatinine (μmol/L) 75.4 ± 16.0 75.6 ± 15.9 75.5 ± 15.2 75.0 ± 17.3 0.485
 Lesion vessels 1.4 ± 0.7 1.4 ± 0.6 1.4 ± 0.7 1.5 ± 0.7  < 0.001
 LM/three-vessel disease, % 2773 (45.2) 567 (40.7) 1224 (42.4) 982 (52.7)  < 0.001
 SYNTAX scorea 12.0 ± 8.2 11.7 ± 7.9 11.7 ± 8.1 12.6 ± 8.5 0.001
 Complete revascularization, % 3310 (53.9) 798 (57.2) 1646 (57.1) 866 (46.5)  < 0.001
 Number of stents 1.8 ± 1.2 1.8 ± 1.1 1.8 ± 1.1 1.9 ± 1.3 0.028
 DES implantation, % 5778 (94.1) 1323 (94.9) 2730 (94.7) 1725 (92.6) 0.006
Medications at discharge, %
 Aspirin 6077 (99.0) 1372(98.4) 2859(99.1) 1846(99.1) 0.067
 Clopidogrel 6020 (98.0) 1366(98.0) 2827(98.0) 1827(98.1) 0.959
 β-blocker 5609 (91.4) 1250(89.7) 2622(90.9) 1737(93.3) 0.001
 ACEI/ARB 3150 (51.3) 697(50.0) 1396(48.4) 1057(56.8)  < 0.001
 CCB 2875 (46.8) 604(43.3) 1341(46.5) 930(49.9) 0.001
 Statin 5923 (96.5) 1332(95.6) 2801(97.1) 1790(96.1) 0.022
 Nitrate 5984 (97.5) 1358(97.4) 2820(97.8) 1806(97.0) 0.240
  1. Values are presented as mean ± standard deviation or number (%)
  2. ACEI angiotensin-converting enzyme inhibitors, ACS acute coronary syndrome, ARB angiotensin II receptor blockers, BMI body mass index, CAD coronary artery disease, CABG coronary artery bypass grafting, CCB calcium channel blocker, DES drug-eluting stent, FIB fibrinogen, FBG fasting blood glucose, hs-CRP high sensitivity C-reactive protein, HbA1c Hemoglobin A1c, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, LM left main disease, LVEF left ventricular ejection fraction, MI myocardial infarction, PCI percutaneous coronary intervention, SAP stable angina pectoris, TC total cholesterol, TG triglycerides
  3. aCalculated using an online calculator (http://www.syntaxscore.com/) by a dedicated research group blinded to the clinical data