Table 1 Baseline characteristics of patients stratified by tertile of TyG index
Total (n = 1574) | Tertile of TyG index | P-value | |||
|---|---|---|---|---|---|
I (Lowest) (n = 525) | II (Median) (n = 533) | III (Highest) (n = 516) | |||
6.55 < TyG ≦ 8.58 | 8.58 < TyG ≦ 9.11 | 9.11 < TyG ≦ 10.89 | |||
Age, years | 58.40 ± 9.40 | 59.54 ± 9.23 | 58.94 ± 9.46 | 56.67 ± 9.28 | < 0.001 |
Male, n (%) | 1218 (77.4) | 423 (80.6) | 406 (76.2) | 389 (75.4) | 0.097 |
BMI, kg/m2 | 25.96 ± 3.23 | 25.28 ± 3.06 | 26.04 ± 3.18 | 26.57 ± 3.32 | < 0.001 |
LVEF, % | 62.17 ± 7.01 | 62.55 ± 6.61 | 61.93 ± 7.14 | 62.04 ± 7.26 | 0.312 |
Diagnosis, n (%) | 0.061 | ||||
UA | 1334 (84.8) | 459 (87.4) | 452 (84.8) | 423(82.0) | |
NSTEMI | 116 (7.4) | 33 (6.3) | 44 (8.3) | 39 (7.6) | |
STEMI | 124 (7.9) | 33 (6.3) | 37 (6.9) | 54 (10.5) | |
Medical history, n (%) | |||||
Current smoking | 556 (35.3) | 173 (33.0) | 184 (34.5) | 199 (38.6) | 0.030 |
Hypertension | 1016 (64.5) | 313 (59.6) | 344 (64.5) | 359 (69.6) | 0.004 |
Hypercholesteraemia | 610 (38.8) | 192 (36.6) | 198 (37.1) | 220 (42.6) | 0.086 |
Diabetes mellitus | 544 (34.6) | 111 (21.1) | 173 (32.5) | 260 (50.4) | < 0.001 |
Previous stroke | 127 (8.1) | 46 (8.8) | 43 (8.1) | 38 (7.4) | 0.710 |
Previous PCI | 289 (18.4) | 95 (18.1) | 108 (20.3) | 86 (16.7) | 0.317 |
Laboratory tests | |||||
Hs-CRP, mg/L | 1.43 (0.56, 3.97) | 0.93 (0.40, 3.11) | 1.44 (0.59, 3.78) | 1.89 (0.82, 4.58) | < 0.001 |
eGFR, mL/min/1.73 m2 | 96.54 ± 14.72 | 96.71 ± 13.93 | 96.56 ± 14.46 | 96.34 ± 15.78 | 0.921 |
Uric acid, umol/L | 345.49 ± 84.69 | 332.35 ± 74.62 | 345.42 ± 81.91 | 358.92 ± 94.61 | < 0.001 |
Homocysteine, umol/L | 12.50 (9.70, 16.10) | 12.80 (9.80, 16.55) | 12.70 (9.85, 16.1) | 12.00 (9.50, 15.68) | 0.095 |
FBG, mmol/L | 6.57 ± 2.31 | 5.50 ± 0.97 | 6.19 ± 1.54 | 8.04 ± 3.06 |  < 0.001 |
Triglycerides, mmol/L | 1.40 (1.02, 1.98) | 0.90 ± 0.26 | 1.47 ± 0.33 | 2.47 ± 0.88 |  < 0.001 |
TC, mmol/L | 4.11 ± 1.07 | 3.75 ± 0.92 | 4.09 ± 0.97 | 4.50 ± 1.17 | < 0.001 |
HDL-C, mmol/L | 1.07 ± 0.24 | 1.15 ± 0.26 | 1.06 ± 0.23 | 0.99 ± 0.21 | < 0.001 |
LDL-C, mmol/L | 2.47 ± 0.89 | 2.24 ± 0.82 | 2.51 ± 0.86 | 2.67 ± 0.93 | < 0.001 |
Angiography | |||||
LM disease, n (%) | 139 (8.8) | 53 (10.1) | 50 (9.4) | 36 (7.0) | 0.179 |
Multivessel/LM disease, n (%) | 1195 (75.9) | 384 (73.1) | 423 (79.4) | 388 (75.2) | 0.055 |
Chronic total occlusion, n (%) | 367 (23.3) | 104 (19.8) | 130 (24.4) | 133 (25.8) | 0.058 |
SYNTAX score | 13.93 ± 7.42 | 13.72 ± 7.83 | 14.36 ± 7.43 | 13.70 ± 6.97 | 0.253 |
Intervention | |||||
Target vessel, n (%) | |||||
LM | 78 (5.0) | 30 (5.7) | 30 (5.6) | 18 (3.5) | 0.175 |
LAD | 889 (56.5) | 304 (57.9) | 296 (55.5) | 289 (56.0) | 0.714 |
LCX | 434 (27.6) | 125 (23.8) | 151 (28.3) | 158 (30.7) | 0.042 |
RCA | 640 (40.7) | 214 (40.8) | 217 (40.7) | 209 (40.5) | 0.996 |
Intracoronary imagine, n (%) | 100 (6.4) | 40 (7.6) | 31 (5.8) | 29 (5.6) | 0.343 |
DES-sirolimus, n (%) | 849 (53.9) | 288 (54.9) | 281 (52.7) | 280 (54.3) | 0.772 |
DES-zotarolimus, n (%) | 345 (21.9) | 127 (24.2) | 117 (22.0) | 101 (19.6) | 0.198 |
DES-everolimus, n (%) | 597 (37.9) | 187 (35.6) | 210 (39.4) | 200 (38.8) | 0.400 |
Number of stent, /patients | 2.00 (1.00, 2.00) | 1.00 (1.00, 2.00) | 2.00 (1.00, 2.00) | 1.00 (1.00, 2.00) | 0.227 |
Multiple stents (n ≥ 2) | 789 (50.1) | 256 (48.8) | 280 (52.5) | 253 (49.0) | 0.392 |
Length of stents, mm/patients | 36 (23, 61) | 36 (21, 58.50) | 38 (23, 62) | 35 (23, 63.75) | 0.223 |
Minimal stent diameter, mm | 2.84 ± 0.46 | 2.88 ± 0.47 | 2.83 ± 0.46 | 2.82 ± 0.46 | 0.105 |
Medications at discharge, n (%) | |||||
Aspirin | 1574 (100.0) | 525 (100.0) | 533 (100.0) | 516 (100.0) | > 0.99 |
Clopidogrel/Ticagrelor | 1574 (100.0) | 525 (100.0) | 533 (100.0) | 516 (100.0) | > 0.99 |
Statin | 1570 (99.7) | 523 (99.6) | 532 (99.8) | 515 (99.8) | 0.779 |
β-block | 1088 (69.2) | 337(64.2) | 378 (71.1) | 373 (72.3) | 0.009 |
ACEI/ARB | 722 (45.9) | 206 (39.2) | 250 (46.9) | 266 (51.6) | < 0.001 |
Insulin | 174 (11.1) | 37 (7.0) | 52 (9.8) | 85 (16.5) | < 0.001 |
Other hypoglycemic agents | 431 (27.4) | 86 (16.4) | 133 (25.0) | 212 (41.1) | < 0.001 |