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Table 3 Determinants of peripheral oxygen extraction

From: Mechanisms of reduced peak oxygen consumption in subjects with uncomplicated type 2 diabetes

  Univariate Multivariate
Variable st-β p st-β p
Age 0.01 ns   
Sex 0.07 0.0138 0.35 0.0002
BMI 0.01 ns   
Duration of diabetes − 0.01 ns   
HbA1c − 0.04 ns   
Smoke 0.02 ns   
Hypertension 0.02 ns   
metformin − 0.01 ns   
Creatinine 0.02 ns   
ACR (log) − 1.02 ns   
PCR (log) − 0.50 ns   
Hemoglobin 0.70 0.0103 0.22 0.0133
RHI endoPAT − 0.06 ns   
CAVI 0.20 ns   
ABI 0.08 ns   
MBP peak − 0.05 0.0175 − 0.02 ns
SVR peak 0.01  < 0.0001 0.01 ns
CO peak − 0.52  < 0.0001 − 0.30 ns
LVEF rest − 0.01 ns   
LVEF peak 0.01 ns   
Δ LVEF 0.10 ns   
GLS rest 0.12 ns   
GLS 4 min 0.34 0.0060 0.10 ns
Δ GLS 0.19  < 0.0001 0.21 0.0486
S’ rest 0.06 ns   
S’ peak 0.06 ns   
Δ S’ 0.16 ns   
E/e’ peak 0.12 ns   
VE/VCO2 slope − 0.06 ns