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Table 2 Serum levels in diabetic patients with and without ICAS

From: Association between carotid plaque vulnerability and high mobility group box-1 serum levels in a diabetic population

Variables

ICAS (n = 347)

WICAS (n = 526)

p value

HMGB1 (ng/mL ± SD)

7.65 ± 13.32

2.96 ± 7.45

< 0.001a

OPG (pmol/L ± SD)

6.86 ± 6.55

3.23 ± 2.25

< 0.001a

Hs-CRP (mg/L ± SD)

16.7 ± 13.2

7.92 ± 3.32

< 0.001a

TNF-alpha (pg/mL ± SD)

63.0 ± 32.2

58.3 ± 21.2

< 0.384a

IL-6 (pg/mL ± SD)

52.4 ± 16.3

34.3 ± 14.5

< 0.001a

  1. ICAS internal carotid artery stenosis; WICAS without internal carotid artery stenosis; SD standard deviation; HMGB1 high-mobility group box 1; OPG osteoprotegerin; Hs-CRP high-sensitivity C-reactive protein; TNF-alpha tumor necrosis factor-alpha; IL-6 interleukin-6
  2. a Statistical test performed with Student’s t test