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Table 2 Serum levels in diabetic patients with and without ICAS

From: Association between carotid plaque vulnerability and high mobility group box-1 serum levels in a diabetic population

Variables ICAS (n = 347) WICAS (n = 526) p value
HMGB1 (ng/mL ± SD) 7.65 ± 13.32 2.96 ± 7.45 < 0.001a
OPG (pmol/L ± SD) 6.86 ± 6.55 3.23 ± 2.25 < 0.001a
Hs-CRP (mg/L ± SD) 16.7 ± 13.2 7.92 ± 3.32 < 0.001a
TNF-alpha (pg/mL ± SD) 63.0 ± 32.2 58.3 ± 21.2 < 0.384a
IL-6 (pg/mL ± SD) 52.4 ± 16.3 34.3 ± 14.5 < 0.001a
  1. ICAS internal carotid artery stenosis; WICAS without internal carotid artery stenosis; SD standard deviation; HMGB1 high-mobility group box 1; OPG osteoprotegerin; Hs-CRP high-sensitivity C-reactive protein; TNF-alpha tumor necrosis factor-alpha; IL-6 interleukin-6
  2. a Statistical test performed with Student’s t test