Skip to main content

Table 1 Demographic and clinical data of study participants

From: Association between carotid plaque vulnerability and high mobility group box-1 serum levels in a diabetic population

 

ICAS (n = 347)

WICAS (n = 526)

p value

Men/female, n

118:229

192:334

0.384b

Age (years ± SD)

72.1 ± 3.9

71.8 ± 3.8

0.157a

Diabetes duration, (years ± SD)

13.3 ± 4.5

12.2 ± 3.4

0.209a

BMI (Kg/m2 ± SD)

30.7 ± 6.3

27.9 ± 4.6

< 0.01a

Smoking (current), n (%)

116 (33.4)

172 (32.7)

0.185b

Smoking (former), n (%)

145 (41.8)

221 (42.0)

0.261b

Hypertension, n (%)

221 (63.7)

215 (40.9)

< 0.01b

CAD, n (%)

189 (54.5)

164 (31.2)

< 0.01b

HIS, n (%)

164 (47.3)

0 (0.0)

< 0.01b

PAD, n (%)

119 (34.3)

113 (21.5)

< 0.01b

Hypercholesterolemia, n (%)

275 (79.3)

153 (29.1)

< 0.01b

LDL-C (mg/dL ± SD)

154 ± 14.6

102 ± 11.2

< 0.01b

Triglycerides (mg/dL ± SD)

194 ± 20.1

139 ± 15.4

< 0.01b

Statins, n (%)

274 (78.9)

156 (29.7%)

< 0.01b

Antihypertensive drugs, n (%)

223 (64.3)

214 (40.7)

< 0.01b

Anti-diabetic treatment

 Diet only, n (%)

36 (10.4)

56 (10.6)

0.349b

 Oral agents, n (%)

169 (48.7)

259 (49.2)

0.328b

 Insulin therapy, n (%)

142 (40.9)

211 (40.2)

0.243b

  1. ICAS internal carotid artery stenosis; WICAS without internal carotid artery stenosis; BMI body mass index; CAD coronary artery disease; HIS history of ischemic stroke; PAD peripheral artery disease; LDL-C low-density lipoprotein cholesterol
  2. aStatistical test performed with Student’s t test
  3. bChi-square test for categorical values