Table 3 Bonferroni significant results of the proteome-wide analysis with incident MetS in KORA (N = 623), sorted by the magnitude of the OR
From: Metabolic syndrome and the plasma proteome: from association to causation
Target full name | UniProt | Gene symbol | OR (CI) | P-value |
|---|---|---|---|---|
Plasminogen activator inhibitor 1 | P05121 | SERPINE1 | 1.82 (1.46–2.30) | 2.28E−07 |
Growth hormone receptor | P10912 | GHR | 1.65 (1.33–2.04) | 4.63E−06 |
Aminoacylase-1 | Q03154 | ACY1 | 1.64 (1.30–2.09) | 4.02E−05 |
C5a anaphylatoxin | P01031 | C5 | 1.62 (1.32–2.01) | 6.52E−06 |
Adiponectin | Q15848 | ADIPOQ | 0.55 (0.43–0.70) | 1.83E−06 |
Insulin-like growth factor-binding protein 2 | P18065 | IGFBP2 | 0.55 (0.44–0.68) | 8.36E−08 |
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 | Q8TEU8 | WFIKKN2 | 0.58 (0.46–0.73) | 4.09E−06 |
Netrin receptor UNC5D | Q6UXZ4 | UNC5D | 0.61 (0.48–0.77) | 2.82E−05 |
Sex hormone-binding globulin | P04278 | SHBG | 0.61 (0.49–0.77) | 3.43E−05 |
Iduronate 2-sulfatase | P22304 | IDS | 0.63 (0.50–0.77) | 1.84E−05 |
Hepatocyte growth factor receptor | P08581 | MET | 0.63 (0.50–0.77) | 1.78E−05 |
Advanced glycosylation end product-specific receptor, soluble | Q15109 | AGER | 0.63 (0.51–0.77) | 1.10E−05 |
Insulin-like growth factor-binding protein 1 | P08833 | IGFBP1 | 0.63 (0.51–0.79) | 4.26E−05 |
Interleukin-1 receptor type 1 | P14778 | IL1R1 | 0.64 (0.52–0.79) | 2.64E−05 |