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Table 1 Baseline characteristics of the study populations

From: Metabolic syndrome and the plasma proteome: from association to causation

Variable

Prevalent MetS

Incident MetS

KORA (n = 998)

HUNT (n = 923)

p value*

KORA (n = 623)

Agea (years)

59.3 (43–75)

68.93 (31.6–91.7)

< 0.001

58.15 (43–74)

Sex femaleb

515 (51.6%)

235 (25.5%)

< 0.001

379 (60.8%)

BMIc (kg/m2)

27.77 (4.58)

28.39 (3.97)

0.002

26.21 (3.87)

Waist circumferencec (cm)

94.56 (14.05)

100.18 (11.04)

< 0.001

89.07 (11.44)

Waist hip ratioc

0.89 (0.08)

0.96 (0.07)

< 0.001

0.86 (0.08)

Physically activeb

620 (62.1%)

468 (50.7%)

< 0.001

416 (66.8%)

Smokingb

  

< 0.001

 

 Never smoker

423 (42.4%)

231 (25%)

 

277 (44.5%)

 Former smoker

427 (42.8%)

497 (53.8%)

 

244 (39.2%)

 Current smoker

148 (14.8%)

195 (21.1%)

 

102 (16.4%)

Total cholesterolc (mg/dl)

221.99 (38.47)

178.50 (42.34)

NA**

222.83 (37.11)

HDL- cholesterolc (mg/dl)

57.35 (15.19)

45.05 (11.25)

NA**

62.84 (14.45)

Triglyceride levelc (mg/dl)

129.06 (87.68)

161.82 (86.81)

NA**

96.59 (46.08)

Hypertensiond

398 (39.9%)

382 (41.4%)

0.544

143 (23.0%)

  1. *Continuous variables were tested for a difference between the two populations using t-tests and categorical variables with chi-square tests with continuity correction, **Differences between cohorts could not be statistically tested as KORA was measured in fasting samples and HUNT in non-fasting samples
  2. aMean (range)
  3. bNumber (percentage)
  4. cMean ± standard deviation. Hypertension was defined as having systolic blood pressure ≥ 140 mmHg and diastolic ≥ 90 mmHg or known medication-controlled hypertension. In HUNT we additionally used the ICD-10 codes I10–I15 of the hospital and primary care data and the codes K86 or K87 of the International Classification of Primary Care, Second Edition, to identify participants with hypertension
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Cardiovascular Diabetology

ISSN: 1475-2840