Skip to main content

Table 2 Multivariable-adjusted associations between skin AF and continuous measures of vascular stiffness in the EPIC-DZD study

From: Advanced glycation end-products, measured as skin autofluorescence, associate with vascular stiffness in diabetic, pre-diabetic and normoglycemic individuals: a cross-sectional study

 

Beta coefficients (95% CI) for skin AF, arbitrary units

cfPWV, m/s

aoPWV, m/s

aoAIx, %

brAIx, %

ABI

Model 1

0.41 (0.24; 0.58)

0.27 (0.16; 0.39)

0.28 (− 0.46; 1.02)

1.49 (− 0.63; 3.62)

− 0.04 (− 0.05; − 0.03)

Model 2

0.38 (0.21; 0.55)

0.25 (0.14; 0.37)

1.00 (0.29; 1.70)

4.12 (2.24; 6.00)

− 0.04 (− 0.05; − 0.02)

  1. N = 3535. Model 1 was adjusted for age and sex. Model 2 was additionally adjusted for BMI, waist circumference, smoking status (three categories: non-smoker, former smoker, current smoker), recreational physical activity (biking and sports, h/week), systolic and diastolic blood pressure, pulse, prevalent conditions (prevalent heart failure, prior myocardial infarction or stroke), antihypertensive and lipid-lowering treatment, CRP, LDL-, HDL- and total cholesterol, triglycerides and HbA1c
  2. EPIC-DZD Sub-study of European Prospective Investigations into Cancer and Nutrition, AF autofluorescence, PWV pulse wave velocity, AIx augmentation index, ABI ankle-brachial index, ao aortic, br brachial, cf carotid-femoral
Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840