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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Sex differences in the association of prediabetes and type 2 diabetes with microvascular complications and function: The Maastricht Study

Fig. 1

Microvascular disease: sex as a determinant versus sex-by-T2D interaction as a determinant. Simulation data to illustrate differences (ad–described below) between sex as a determinant and sex-by-T2D interaction as a determinant for microvascular disease. Precise prevalences will vary in real data. Black circles represent women and white squares represent men. NGM: normal glucose metabolism; T2D: type 2 diabetes Microvascular disease: #investigation of sex as a determinant; + women with T2D vs. women with NGM; men with T2D vs. men with NGM; * investigation of sex-by-T2D interaction as a determinant. Statistically significantly differences (# and/or * p < 0.05) are typed in bold. A: Sex is a determinant in neither NGM nor T2D; the sex-by-T2D interaction is not a determinant. B: Sex is a determinant in T2D but not in NGM; hence the sex-by-T2D interaction is a determinant. C: Sex is a determinant in NGM but not in T2D; hence (!) the sex-by-T2D interaction is a determinant. D: Sex is a determinant in both NGM and T2D; the sex-by-T2D interaction is not a determinant

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