Skip to main content

Table 2 Summary of the studies showing an effect of lipids variability on the development of complications in patients with diabetes

From: Variability of risk factors and diabetes complications

Risk factor Type of variability assessed Short or long term variability Metrics used Type of study Sample size Significantly associated outcomes Follow-up length References
LDL Visit-to-visit Long-term Standard deviation Observational cohort 162 Carotid intima-media thickness 1 year [21]
Observational cohort 5354 Cardiovascular events 3.2 years [22]
Observational cohort 1792 Cardiovascular events 65 months [23]
HDL Visit-to-visit Long-term Standard deviation Observational cohort 1792 Cardiovascular events 65 months [23]
Observational cohort 864 Appearance of albuminuria 3 years [24]
Non-HDL cholesterol Visit-to-visit Long-term Standard deviation Observational cohort 1792 Cardiovascular events 65 months [23]
Triglycerides Visit-to-visit Long-term Standard deviation Observational cohort 457 Incident microalbuminuria 6.8-years [27]
Post-prandial Short-term Coefficient of variation Observational cohort 168 eGFR decline 6.0 years [26]