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Table 2 Odds ratios for MACE associated with quartiles of coefficient of variation of SBP/DBP

From: Predictive value of visit-to-visit blood pressure variability for cardiovascular events in patients with coronary artery disease with and without diabetes mellitus

 

Quartiles of CV

P trend

Q1

Q2

Q3

Q4

Systolic blood pressure

Events, n (%)

27 (9)

41 (14)

40 (14)

84 (29)

 
 

OR (95% CI)

 

Model 1

1.00 (reference)

1.70 (1.00–2.88)†

1.63 (0.95–2.81)

3.77 (2.27–6.26)*

 < 0.001

Model 2

1.00 (reference)

1.59 (0.93–2.72)

1.40 (0.80–2.43)

3.25 (1.94–5.45)*

 < 0.001

Model 3

1.00 (reference)

1.60 (0.94–2.75)

1.43 (0.82–2.48)

3.30 (1.97–5.54)*

 < 0.001

Diastolic blood pressure

Events, n (%)

26 (9)

41 (14)

55 (19)

70 (25)

 
 

OR (95% CI)

 

Model 1

1.00 (reference)

1.78 (1.03–3.05)†

2.35 (1.38–4.00)*

2.83 (1.68–4.79)*

 < 0.001

Model 2

1.00 (reference)

1.72 (0.99–2.99)

2.09 (1.21–3.60)*

2.54 (1.49–4.35)*

0.001

Model 3

1.00 (reference)

1.66 (0.96–2.89)

1.97 (1.13–3.41)†

2.39 (1.39–4.11)*

0.002

  1. Model 1 is adjusted for age, sex and number of BP measurements (ln-transformed)
  2. Model 2 is adjusted for variables in model 1 and type 2 diabetes, hypertension and beta-blockers
  3. Model 3 is adjusted for variables in model 2 and mean SBP or DBP
  4. CI confidence interval, CV coefficient of variation, DBP diastolic blood pressure, OR odds ratio, SBP systolic blood pressure
  5. †P < 0.05; *P < 0.01