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Table 3 Risk of developing each cardiovascular morbidity according to the presence of CKD after DM or not, based on a restrictive CKD diagnostic code set (n = 54,224 per group)

From: The risk trajectory of different cardiovascular morbidities associated with chronic kidney disease among patients with newly diagnosed diabetes mellitus: a propensity score-matched cohort analysis

Outcomes

Events

Person-year

Incidence density*

Crude

Model A&

HR

95% CI

HR

95% CI

Mortality

Matched control

5853

231,470.74

25.29

1

–

1

–

CKD after DM

5985

230,546.27

25.96

1.026

0.99–1.06

1.098

1.06–1.14c

Heart failure

Matched control

1179

229,256.82

5.14

1

–

1

–

CKD after DM

1523

227,644.35

6.69

1.301

1.21–1.40c

1.282

1.19–1.38c

Acute myocardial infarction

Matched control

575

230,252.1

2.50

1

–

1

–

CKD after DM

637

229,347.34

2.78

1.112

0.99–1.25

1.147

1.02–1.29a

Peripheral vascular disease

Matched control

227

230,979.43

0.98

1

–

1

–

CKD after DM

291

230,007.4

1.27

1.288

1.08–1.53b

1.279

1.07–1.52b

Ischemic stroke

Matched control

1414

228,115.7

6.20

1

–

1

–

CKD after DM

1413

227,280.79

6.22

1.003

0.93–1.08

1.013

0.94–1.09

Hemorrhagic stroke

Matched control

392

230,755.67

1.70

1

–

1

–

CKD after DM

385

229,933.54

1.67

0.986

0.86–1.14

0.958

0.83–1.10

Atrial fibrillation

Matched control

1016

229,503.21

4.43

1

–

1

–

CKD after DM

1095

228,537.21

4.79

1.083

0.99–1.18

1.053

0.97–1.15

  1. CI confidence interval, CKD chronic kidney disease, DM diabetes mellitus, HR hazard ratio
  2. * per 1000 patient-year
  3. & Incorporating age/gender, lifestyle factors, all comorbidities, and all medications
  4. a p < 0.05
  5. b p < 0.01
  6. c p < 0.001
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Cardiovascular Diabetology

ISSN: 1475-2840