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Table 2 Association of the TyG index and HOMA-IR with baPWV

From: Stronger association of triglyceride glucose index than the HOMA-IR with arterial stiffness in patients with type 2 diabetes: a real-world single-centre study

 

BaPWV, m/s

Model 1

Model 2

Model 3

β (95% CI)

P value

β (95% CI)

P value

β (95% CI)

P value

TyG index

0.74 (0.59, 0.89)

< 0.001

0.31 (0.14, 0.48)

< 0.001

0.38 (0.21, 0.55)

< 0.001

Tertile 1

Reference

Reference

Reference

Tertile 2

0.52 (0.27, 0.77)

< 0.001

0.25 (− 0.01, 0.50)

0.055

0.28 (0.02, 0.54)

0.032

Tertile 3

1.16 (0.90, 1.41)

< 0.001

0.40 (0.12, 0.68)

0.006

0.50 (0.21, 0.79)

< 0.001

P for trend

< 0.001

0.006

< 0.001

HOMA-IR

0.02 (0.01, 0.02)

< 0.001

0.01 (0.001, 0.01)

0.032

0.01 (0.001, 0.01)

0.029

Tertile 1

Reference

Reference

Reference

Tertile 2

0.49 (0.23, 0.75)

< 0.001

0.13 (− 0.12, 0.38)

0.316

0.16 (− 0.09, 0.42)

0.210

Tertile 3

0.88 (0.62, 1.14)

< 0.001

0.29 (0.01, 0.56)

0.042

0.34 (0.06, 0.62)

0.017

P for trend

< 0.001

0.042

0.017

P valuea

< 0.001

 

< 0.001

 

< 0.001

 
  1. Data was regression coefficient (β) and 95% confidence interval (CI), evaluated using generalized linear models. P valuea was calculated by using seemingly unrelated regression estimation to compare the regression coefficient (β) between TyG index and HOMA-IR
  2. Model 1: adjusted for age and sex
  3. Model 2: model 1 + adjusted for BMI, waist circumference, systolic blood pressure, LDL-C, HDL-C and WBC counts
  4. Model 3: model 2 + adjusted for smoking status, drinking status, lipid lowering agents, antihypertensive agents, insulin therapy, non-insulin hypoglycemic agents
  5. TyG triglyceride glucose index, HOMA-IR homeostasis model assessment for insulin resistance, baPWV brachial to ankle pulse wave velocity