Table 2 Cox regression analyses of NT-proBNP for predicting MACEs according to glucose status at baseline

Overall^a

 LgNT-proBNP (per 1-SD)

2.82 (2.21–3.60)^‡

1.61 (1.35–1.91)^‡

 Tertile 1 (< 92.5 pg/mL)

1.00 (reference)

1.00 (reference)

 Tertile 2 (92.5-491.1 pg/mL)

2.10 (1.45–3.03)^‡

1.89 (1.24–2.86)^†

 Tertile 3 (> 491.1 pg/mL)

3.24 (2.29–4.60)^‡

2.65 (1.77–3.98)^‡

Normoglycemia

 LgNT-proBNP (per 1-SD)

1.32 (1.05–1.66)*

1.12 (0.76–1.65)

 Tertile 1 (< 65.5 pg/mL)

1.00 (reference)

1.00 (reference)

 Tertile 2 (65.5-405.8 pg/mL)

1.37 (0.77–2.44)

1.31 (0.73–2.35)

 Tertile 3 (> 405.8 pg/mL)

1.65 (0.96–2.85)

1.50 (0.83–2.71)

Pre-DM

 LgNT-proBNP (per 1-SD)

1.96 (1.54–2.50)^‡

1.61 (1.23–2.12)^‡

 Tertile 1 (< 101.8 pg/mL)

1.00 (reference)

1.00 (reference)

 Tertile 2 (101.8–507.0 pg/mL)

2.59 (1.45–4.64)*

2.39 (1.25–4.55)^†

 Tertile 3 (> 507.0 pg/mL)

3.64 (2.07–6.39)^‡

2.56 (1.34–4.91)^†

DM

  LgNT-proBNP (per 1-SD)

1.92 (1.52–2.42)^‡

1.69 (1.30–2.21)^‡

  Tertile 1 (< 110.6 pg/mL)

1.00 (reference)

1.00 (reference)

  Tertile 2 (110.6-518.8 pg/mL)

1.64 (1.11–2.75)*

1.51 (1.04–2.20)*

  Tertile 3 (> 518.8 pg/mL)

2.60 (1.59–4.24)^‡

2.34 (1.32–4.16)^‡