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Table 2 Comparisons of CMR findings between controls, HTN (T2DM −) group and HTN (T2DM +) group

From: Impact of type 2 diabetes mellitus on left ventricular diastolic function in patients with essential hypertension: evaluation by volume-time curve of cardiac magnetic resonance

 

Controls

HTN (T2DM−)

HTN (T2DM +)

P value

n = 52

n = 76

n = 48

 

CMR-derived cardiac geometric and functional parameters

 Heart rate (beats/min)

69.2 ± 11.3

73.5 ± 14.3

71.82 ± 12.33

0.196

 LVEF (%)

70.8 ± 4.9

71.3 ± 8.1

69 ± 9.3

0.326

 LVEDVI (ml/m2)

68.21 ± 12.09

70.16 ± 14.8

70.24 ± 11.76

0.702

 LVESVI (ml/m2)

20.33 ± 7.27

20.91 ± 9.56

22.06 ± 8.47

0.626

 LVSVI (ml/m2)

47.89 ± 6.71

49.25 ± 8.33

48.18 ± 9.25

0.641

LVMASS(g)

83.30 ± 23.23

102.4 ± 33.3*

100.4 ± 27.50*

0.000

Standardized Left Ventricular Mass(g/m2)

47.92 ± 12.16

59.7 ± 15.65*

56.6 ± 15.4*

0.000

LV-remodeling index (g/ml)

0.73 ± 0.15

0.83 ± 0.14*

0.89 ± 0.16*

0.000

CMR volume-time curve parameters of left ventricle

 PER (ml/s)

387.48 ± 99.63

417.89 ± 115.86

384.42 ± 92.66

0.088

 PET (ms)

109.07 ± 23.84

103.46 ± 29.01

110.76 ± 30.52

0.116

 PFR (ml/s)

390.61 ± 84.98

357.8 ± 95.9*

319.8 ± 67.8*,#

0.000

 PFT (ms)

124.88 ± 24.43

149.14 ± 41.80*

158.42 ± 36.9*

0.000

 PER/EDV

3.26 ± 0.62

3.57 ± 0.89

3.49 ± 0.66

0.154

 PFR/EDV

3.45 ± 0.55

3.05 ± 0.75*

2.78 ± 0.69*,#

0.000

CMR strain parameters of left ventricle

 PS (%)

    

 Radial

38.89 ± 8.37

37.57 ± 12.22

36.0 ± 10.59

0.552

 Circumferential

− 21.1 ± 2.86

− 21.1 ± 2.89

− 20.26 ± 3.68

0.170

 Longitudinal

− 15.13 ± 2.64

-13.90 ± 2.83*

− 11.91 ± 3.62*,#

0.004

 PSSR (1/s)

    

 Radial

1.94 ± 0.58

2.11 ± 0.79

2.06 ± 0.99

0.822

 Circumferential

− 1.01 ± 0.20

− 1.08 ± 0.27

− 0.92 ± 0.50#

0.041

 Longitudinal

− 0.68 ± 0.34

− 0.81 ± 0.25

− 0.61 ± 0.5

0.232

PDSR (1/s)

 Radial

− 2.62 ± 1.30

− 2.54 ± 1.27

− 2.09 ± 0.90*

0.031

 Circumferential

1.30 ± 0.26

1.41 ± 0.38

1.12 ± 0.23*,#

0.007

 Longitudinal

0.91 ± 0.26

0.96 ± 0.28

0.84 ± 0.33

0.574

  1. HTN hypertension, T2DM type 2 diabetes mellitus, LV left ventricular, EF ejection fraction, EDV end diastolic volume, ESV end systolic volume, SV stroke volume, I indexed to BSA, PET time to peak ejection rate, PFT time to peak filling rate from end-systole, PER peak ejection rate, PFR peak filling rate, PS peak strain, PSSR peak systolic strain rate, PDSR peak diastolic strain rate
  2. *p < 0.05 versus controls;
  3. #p < 0.05 versus HTN (T2DM-) group
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Cardiovascular Diabetology

ISSN: 1475-2840