| Prior CVD (n = 89,920) | Diabetes only (n = 46,032) | CKD only (n = 13,459) | Diabetes and CKD (n = 13,319) |
---|---|---|---|---|
Myocardial infarction | ||||
 Number of events | 14,350 | 5725 | 1894 | 2562 |
 Incidence Rate (95% CI) | 84 (82, 85) | 63 (62, 64) | 85 (81, 89) | 117 (113, 122) |
Hazard ratio (95% CI) | ||||
 Model 1 | 1.00 (ref) | 0.83 (0.80–0.85) | 0.89 (0.85–0.94) | 1.30 (1.24–1.35) |
 Model 2 | 1.00 (ref) | 0.88 (0.85–0.91) | 0.92 (0.87–0.96) | 1.25 (1.20–1.31) |
Coronary heart disease | ||||
 Number of events | 18,741 | 8055 | 2266 | 3051 |
 Incidence Rate (95% CI) | 114 (113, 116) | 92 (90, 94) | 105 (100, 109) | 145 (140, 150) |
Hazard ratio (95% CI) | ||||
 Model 1 | 1.00 (ref) | 0.85 (0.82–0.87) | 0.86 (0.82–0.90) | 1.20 (1.16–1.25) |
 Model 2 | 1.00 (ref) | 0.91 (0.88–0.94) | 0.90 (0.86–0.94) | 1.19 (1.14–1.24) |
Stroke | ||||
 Number of events | 3019 | 1342 | 401 | 469 |
 Incidence Rate (95% CI) | 16 (16, 17) | 14 (13, 15) | 17 (15, 18) | 19 (18, 21) |
Hazard ratio (95% CI) | ||||
 Model 1 | 1.00 (ref) | 0.98 (0.91–1.04) | 0.87 (0.79–0.97) | 1.11 (1.01–1.23) |
 Model 2 | 1.00 (ref) | 1.00 (0.93–1.08) | 0.87 (0.78–0.97) | 1.09 (0.98–1.20) |
Peripheral artery disease | ||||
 Number of events | 1238 | 577 | 104 | 241 |
 Incidence Rate (95% CI) | 7 (6, 7) | 6 (5, 6) | 4 (3, 5) | 10 (9, 11) |
Hazard ratio (95% CI) | ||||
 Model 1 | 1.00 (ref) | 0.85 (0.77–0.94) | 0.65 (0.53–0.79) | 1.32 (1.15–1.52) |
 Model 2 | 1.00 (ref) | 0.92 (0.83–1.03) | 0.66 (0.54–0.81) | 1.28 (1.11–1.49) |