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Fig. 2 | Cardiovascular Diabetology

Fig. 2

From: MicroRNAs and long non-coding RNAs in the pathophysiological processes of diabetic cardiomyopathy: emerging biomarkers and potential therapeutics

Fig. 2

The possible therapeutic mechanism of lncRNAs-contributed to the oxidative stress, inflammation and cardiac function process in diabetic cardiomyopathy. CASP-1 Caspase 1, CK-MB creatine kinase myocardial band, GSDMD-N N-terminal of gasdermin D, HMGB1 high mobility group box 1, HOTAIR HOX transcript antisense intergenic RNA, IL interleukin, Kcnq1ot1 KCNQ1 overlapping transcript 1, LDH lactate dehydrogenase, LncRNA long non-coding RNA, MALAT1 metastasis-associated lung adenocarcinoma 1, miR microRNA, mRNA messenger RNA, NLRP3 nod-like receptor protein 3, NF-κB nuclear factor kappa-light-chain-enhancer of activated B cells, ROS reactive oxygen species, SAA3 serum amyloid antigen 3, SIRT1 Sirtuin 1, TLR4 toll-like receptor 4, TNFα transforming growth factor β, VDAC1 voltage-dependent anion channel 1

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Cardiovascular Diabetology

ISSN: 1475-2840