Table 4 HRs for risk of outcomes according to quartiles of updated cumulative average TyG index

Stroke

 Case, n (%)

1056 (4.33)

1157 (4.74)

1291 (5.29)

1618 (6.63)

 Incidence, per 1000 person-y

4.18

4.54

5.06

6.42

  Model 1

Reference

1.12 (1.03–1.22)

1.27 (1.17–1.37)

1.71 (1.58–1.85)

  Model 2

Reference

1.06 (0.98–1.16)

1.16 (1.06–1.26)

1.50 (1.38–1.63)

  Model 3

Reference

1.01 (0.93–1.10)

1.05 (0.96–1.14)

1.25 (1.15–1.36)

Ischemic stroke

 Case, n (%)

830 (3.40)

963 (3.94)

1089 (4.46)

1395 (5.71)

 Incidence, per 1000 person-y

3.27

3.76

4.25

5.51

  Model 1

Reference

1.19 (1.08–1.31)

1.37 (1.25–1.50)

1.89 (1.73–2.06)

  Model 2

Reference

1.13 (1.03–1.24)

1.25 (1.14–1.37)

1.66 (1.51–1.81)

  Model 3

Reference

1.07 (0.98–1.18)

1.13 (1.03–1.24)

1.39 (1.27–1.52)

Intracerebral hemorrhage

 Case, n (%)

219 (0.90)

203 (0.83)

214 (0.88)

244 (1.00)

 Incidence, per 1000 person-y

0.85

0.78

0.83

0.95

  Model 1

Reference

0.94 (0.78–1.14)

1.00 (0.83–1.21)

1.20 (1.00–1.44)

  Model 2

Reference

0.89 (0.73–1.08)

0.92 (0.76–1.11)

1.06 (0.88–1.29)

  Model 3

Reference

0.85 (0.70–1.03)

0.83 (0.68–1.00)

0.89 (0.73–1.08)