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Table 3 HRs for risk of outcomes according to quartiles of baseline TyG index

From: Triglyceride-glucose index and the risk of stroke and its subtypes in the general population: an 11-year follow-up

Outcomes

TyG index

P value for trend

Quartile 1 (3.61–8.18)

Quartile 2 (8.18–8.57)

Quartile 3 (8.57–9.05)

Quartile 4 (9.05–12.50)

Stroke

     

 Case, n (%)

922 (3.78)

1139 (4.67)

1403 (5.75)

1658 (6.79)

 

 Incidence, per 1000 person-y

3.60

4.48

5.54

6.59

 

  Model 1

Reference

1.20 (1.10–1.31)

1.46 (1.35–1.59)

1.79 (1.65–1.93)

< 0.001

  Model 2

Reference

1.14 (1.05–1.25)

1.34 (1.23–1.46)

1.58 (1.45–1.72)

< 0.001

  Model 3

Reference

1.08 (0.99–1.18)

1.22 (1.12–1.33)

1.32 (1.21–1.44)

< 0.001

Ischemic stroke

     

 Case, n (%)

725 (2.97)

944 (3.87)

1183 (4.85)

1425 (5.84)

 

 Incidence, per 1000 person-y

2.82

3.70

4.65

5.64

 

  Model 1

Reference

1.26 (1.15–1.39)

1.57 (1.43–1.72)

1.96 (1.79–2.14)

< 0.001

  Model 2

Reference

1.21 (1.10–1.33)

1.44 (1.31–1.58)

1.73 (1.58–1.90)

< 0.001

  Model 3

Reference

1.14 (1.03–1.26)

1.31 (1.19–1.44)

1.45 (1.31–1.59)

< 0.001

Intracerebral hemorrhage

     

 Case, n (%)

190 (0.78)

193 (0.79)

244 (1.00)

253 (1.04)

 

 Incidence, per 1000 person-y

0.73

0.75

0.95

0.98

 

  Model 1

Reference

0.98 (0.80–1.20)

1.22 (1.01–1.48)

1.30 (1.07–1.56)

< 0.001

  Model 2

Reference

0.93 (0.76–1.14)

1.13 (0.93–1.37)

1.16 (0.95–1.41)

0.04

  Model 3

Reference

0.89 (0.73–1.09)

1.03 (0.85–1.25)

0.97 (0.79–1.18)

0.84

  1. Model 1, adjusted for age and sex
  2. Model 2, adjusted for variables in model 1 plus level of education, income, smoking, alcohol abuse, physical activity, and body mass index
  3. Model 3, adjusted for variables in model 2 plus systolic blood pressure, diastolic blood pressure, history of myocardial infarction, hypertension, diabetes mellitus, and dyslipidemia, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, high-sensitive C-reactive protein, antidiabetic drugs, lipid-lowering drugs and antihypertensive drugs
  4. TyG indicates triglyceride-glucose