Table 2 Baseline characteristics according to quartiles of updated cumulative average TyG index
Variable | Total | TyG index | P value | |||
|---|---|---|---|---|---|---|
Quartile 1 (4.67–8.31) | Quartile 2 (8.31–8.65) | Quartile 3 (8.65–9.06) | Quartile 4 (9.06–12.20) | |||
Participants, n | 97,653 | 24,413 | 24,413 | 24,414 | 24,413 | Â |
Age, years | 51.67 (43.53–58.97) | 51.61 (42.65–60.31) | 51.79 (43.61–59.21) | 52.03 (44.05–58.95) | 51.27 (43.63–57.64) | < 0.001 |
Male, n (%) | 77,748 (79.62) | 18,539 (75.94) | 19,345 (79.24) | 19,642 (80.45) | 20,222 (82.83) | < 0.001 |
High school or above, n (%) | 19,064 (20.21) | 5375 (22.75) | 4559 (19.29) | 4626 (19.66) | 4504 (19.15) | < 0.001 |
Income > 800 Renminbi/month, n (%) | 13,466 (14.29) | 3481 (14.74) | 3214 (13.61) | 3374 (14.35) | 3397 (14.44) | 0.004 |
Body mass index, kg/m2 | 24.84 (22.60–27.22) | 23.04 (21.05–25.26) | 24.39 (22.41–26.61) | 25.45 (23.43–27.64) | 26.37 (24.34–28.51) | < 0.001 |
Systolic blood pressure, mm Hg | 130.00 (119.30–140.70) | 120.70 (110.00–138.70) | 129.00 (116.70–140.00) | 130.00 (120.00–144.00) | 130.00 (120.00–150.00) | < 0.001 |
Diastolic blood pressure, mm Hg | 80.00 (78.70–90.00) | 80.00 (70.70–86.00) | 80.00 (76.70–90.00) | 80.70 (79.30–90.00) | 83.30 (80.00–91.30) | < 0.001 |
Current smoker, n (%) | 32,577 (34.26) | 7628 (32.10) | 7667 (32.23) | 8240 (34.72) | 9042 (37.99) | < 0.001 |
Current alcohol use, n (%) | 35,613 (37.44) | 8539 (35.91) | 8288 (34.83) | 9038 (38.08) | 9748 (40.95) | < 0.001 |
Active physical activity, n (%) | 85,899 (91.27) | 21,705 (92.04) | 21,528 (91.32) | 21,325 (90.85) | 21,341 (90.87) | < 0.001 |
Myocardial infarction, n (%) | 1105 (1.13) | 214 (0.88) | 276 (1.13) | 289 (1.18) | 326 (1.34) | < 0.001 |
Diabetes Mellitus, n (%) | 2860 (2.93) | 139 (0.57) | 329 (1.35) | 614 (2.52) | 1778 (7.28) | < 0.001 |
Hypertension, n (%) | 11,450 (11.73) | 1700 (6.96) | 2419 (9.91) | 3224 (13.21) | 4107 (16.82) | < 0.001 |
Hypercholesterolemia, n (%) | 5429 (5.56) | 631 (2.59) | 1041 (4.26) | 1440 (5.90) | 2317 (9.49) | < 0.001 |
Fasting plasma glucose, mmol/L | 5.11 (4.66–5.71) | 4.84 (4.45–5.26) | 5.03 (4.61–5.50) | 5.20 (4.73–5.80) | 5.60 (5.00–6.70) | < 0.001 |
Triglycerides, mmol/L | 1.27 (0.89–1.93) | 0.76 (0.60–0.96) | 1.13 (0.92–1.38) | 1.51 (1.19–1.93) | 2.43 (1.75–3.56) | < 0.001 |
HDL-C, mmol/L | 1.51 (1.28–1.77) | 1.55 (1.31–1.81) | 1.53 (1.30–1.78) | 1.49 (1.27–1.74) | 1.45 (1.24–1.72) | < 0.001 |
LDL-C, mmol/L | 2.33 (1.82–2.83) | 2.15 (1.63–2.71) | 2.36 (1.90–2.81) | 2.40 (1.96–2.90) | 2.39 (1.85–2.90) | < 0.001 |
Hs-CRP, mg/L | 0.80 (0.30–2.19) | 0.59 (0.20–1.70) | 0.72 (0.29–2.00) | 0.89 (0.33–2.25) | 1.10 (0.45–2.72) | < 0.001 |
TyG index | 8.58 (8.18–9.05) | 8.00 (7.74–8.23) | 8.43 (8.22–8.62) | 8.77 (8.53–9.01) | 9.35 (9.03–9.76) | < 0.001 |
Antidiabetic drugs, n (%) | 2185 (2.24) | 97 (0.40) | 229 (0.94) | 488 (2.00) | 1371 (5.62) | < 0.001 |
Lipid-lowering drugs, n (%) | 796 (0.82) | 81 (0.33) | 148 (0.61) | 204 (0.84) | 363 (1.49) | < 0.001 |
Antihypertensive drugs, n (%) | 9895 (10.13) | 1446 (5.92) | 2094 (8.58) | 2809 (11.51) | 3546 (14.53) | < 0.001 |