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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: Activation of the cardiac non-neuronal cholinergic system prevents the development of diabetes-associated cardiovascular complications

Fig. 3

The characteristics of db/db-ChAT-tg mice. a Representative blots and quantitative bar graphs with scatter plots showing the protein expression of ChAT in the diabetic (db/db) and db/db-ChAT-tg heart at early and established stage of diabetes. A non-parametric Kruskal–Wallis test with Bunn’s test was performed. b The quantitative bar graphs with scatter plots showing the cardiac ACh content in the db/db and db/db-ChAT-tg mice at early and established stage of diabetes. Two way-ANOVA was performed. c Quantitative bar graphs with scatter plots showing the changes in body weight between the db/db and db/db-ChAT-tg mice at early and established stage of diabetes. Two-way ANOVA with Tukey’s test for multiple comparisons was performed. Data are expressed as mean ± SEM. #p < 0.05 and ####P < 0.0001 compared to age-matched db/db mice as indicated. The numbers in the bars represent the number of samples and animals analyzed per group

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