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Table 1 General features of the eligible studies

From: Long-term prognosis of chronic total occlusion treated by successful percutaneous coronary intervention in patients with or without diabetes mellitus: a systematic review and meta-analysis

Studies

Country/Region

Year

Study type/Patients enrollment period

Multicenter

Study patients

Stent

Study quality

Liu et al

Japan

2013

Respective cohort study/

2005–2009

NO

Successful CTO PCI:

DM/ Non-DM:51/102

DES:62.9%, BMS:31.4%

8

Claessen

United states, South Korea, and Italy

2011

Prospective cohort study/

1998–2007

YES

1.Successful CTO PCI:

DM/ Non-DM: 202/528

2. DM (395)

Failed/successful PCI: 120/275

Non-DM (1347)

Failed/successful PCI:

432/915

1.DES:100%

2.DES: more than 60%

8

Sohrabi et al

Iran

2011

Prospective cohort study/

2009–2011

NO

Successful CTO PCI:

DM/ Non-DM:34/129

DES:NA, BMS: NA

8

Ruiz-Garcia

Spain and Portugal

2015

RCT/NA

YES

Successful CTO PCI:

DM/Non-DM:75/132

DES: 100%

4

Rha et al

Korea

2015

Respective cohort study/

2007–2009

YES

Successful CTO PCI:

DM/Non-DM: 920/920

DES:100%

8

Yang et al

China

2020

Prospective cohort study/

2016–2018

NO

Successful CTO PCI:

DM/Non-DM:198/335

DES:100%

8

Sanguineti et al

France

2017

Prospective cohort study/

2004–2012

NO

DM(362):

Failed /successful PCI:

103/259

Non-DM (958):

Failed /successful PCI: 227/731

DES: more than 90%

9

Tsai et al

Taiwan

2020

Respective cohort study/

2005–2015

NO

DM (313)

Failed/successful PCI:

48/265

Non-DM(426)

Failed/successful PCI:

72/354

NA

8

Guo et al

China

2020

Respective cohort study/

2007–2018

NO

DM (755)

PCI / initial MT: 249/506

Non-DM (1260)

PCI / initial MT: 469/791

Almost all DES

8

Yan et al

China

2019

Respective cohort study/

2007–2017

NO

DM (733)

PCI/CTO-MT:

309/424

Almost all DES

7

Flores-Umanzor et al

Spain

2020

Prospective cohort study/

2010–2014

NO

DM (402)

PCI/CTO-MT:

76/326

DES:100%

8

  1. CTO chronic total occlusion, PCI percutaneous coronary intervention, DM Diabetes mellitus, DES,drugs-eluting stent, BMS bare metal stent, NA not available, RCT randomized controlled trials, MT medical treatment. CTO-MT consists of initial MT and failed CTO-PCI