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Table 3 Risk of myocardial infarction, ischemic stroke, and all-cause death in patients with diabetes and their matched general population comparison cohort

From: Ten-year cardiovascular risk in diabetes patients without obstructive coronary artery disease: a retrospective Western Denmark cohort study

 

Patients

Events

10-year cumulative incidencea (95% CI)

Risk differencea

(95% CI)

Unadjusted HR (95% CI)

Adjusted HRb (95% CI)

Adjusted HRc (95% CI)

Myocardial infarction

 General population

28,670

595

2.9% (2.7–3.1)

Reference

Reference

Reference

Reference

 Diabetes patients

5734

134

3.2% (2.7–3.8)

0.3% (-0.3–0.9)

1.26 (1.04–1.52)

1.07 (0.84–1.36)

0.93 (0.72–1.20)

Ischemic stroke

 General population

28,670

456

2.2% (2.0–2.4)

Reference

Reference

Reference

Reference

 Diabetes patients

5734

230

5.2% (4.5–5.9)

3.0% (2.3–3.7)

2.96 (2.51–3.50)

2.04 (1.65–2.52)

1.87 (1.47–2.38)

Death

 General population

28,670

3659

17.8% (17.2–18.3)

Reference

Reference

Reference

Reference

 Diabetes patients

5734

1228

29.6% (28.1–31.1)

11.8% (10.2–13.4)

1.88 (1.76–2.01)

1.58 (1.45–1.72)

1.24 (1.13–1.36)

  1. CAG coronary angiography, CI confidence interval, CIP cumulative incidence proportion, HR hazard ratio
  2. aLimited to the 75th percentile of follow-up (10 years). In myocardial infarction and ischemic stroke, accounting for the competing risk of death
  3. bAdjusted for myocardial infarction within 30 days of angiography, statin treatment, oral anticoagulant treatment, and antiplatelet treatment
  4. cAdjusted for peripheral artery disease, hypertension, chronic obstructive pulmonary disease, myocardial infarction within 30 days of angiography, statin treatment, oral anticoagulant treatment, and antiplatelet treatment. In case of ischemic stroke and death, additionally adjusted for congestive heart failure, previous ischemic stroke/TIA, and atrial fibrillation