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Table 1 Animal characteristics

From: Load-independent effects of empagliflozin contribute to improved cardiac function in experimental heart failure with reduced ejection fraction

 Sham + controlSham + empaMI + vehicleMI + empa
Body weight (g)288 ± 4267 ± 2*271 ± 3*257 ± 2*,†
Haemoglobin (g/L)131 ± 7144 ± 3*143 ± 2*150 ± 3
Plasma sodium (mmol/L)126 ± 2128 ± 3131 ± 1*133 ± 1
HbA1c (%)4.8 ± 0.25.0 ± 0.14.7 ± 0.14.9 ± 0.1
HW indexed to tibial length (mg/mm)18.1 ± 0.417.2 ± 0.318.9 ± 0.616.7 ± 0.3
Lung weight indexed to tibial length (mg/mm)25 ± 125 ± 131 ± 324 ± 1
  1. Data are expressed as mean ± SEM
  2. N = 13–15 in sham Control and sham + Empagliflozin groups; N = 20 and 20 in MI Control and MI + Empagliflozin groups, respectively
  3. Empa empagliflozin, LV weight/TL Left ventricular weight/tibial length, LW/TL lung weight/tibial length ratio
  4. * p < 0.05 vs. sham control group
  5. p < 0.05 vs. MI control group