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Table 1 Animal characteristics

From: Load-independent effects of empagliflozin contribute to improved cardiac function in experimental heart failure with reduced ejection fraction

 

Sham + control

Sham + empa

MI + vehicle

MI + empa

Body weight (g)

288 ± 4

267 ± 2*

271 ± 3*

257 ± 2*,†

Haemoglobin (g/L)

131 ± 7

144 ± 3*

143 ± 2*

150 ± 3†

Plasma sodium (mmol/L)

126 ± 2

128 ± 3

131 ± 1*

133 ± 1†

HbA1c (%)

4.8 ± 0.2

5.0 ± 0.1

4.7 ± 0.1

4.9 ± 0.1

HW indexed to tibial length (mg/mm)

18.1 ± 0.4

17.2 ± 0.3

18.9 ± 0.6

16.7 ± 0.3†

Lung weight indexed to tibial length (mg/mm)

25 ± 1

25 ± 1

31 ± 3

24 ± 1†

  1. Data are expressed as mean ± SEM
  2. N = 13–15 in sham Control and sham + Empagliflozin groups; N = 20 and 20 in MI Control and MI + Empagliflozin groups, respectively
  3. Empa empagliflozin, LV weight/TL Left ventricular weight/tibial length, LW/TL lung weight/tibial length ratio
  4. * p < 0.05 vs. sham control group
  5. †p < 0.05 vs. MI control group
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Cardiovascular Diabetology

ISSN: 1475-2840