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Table 1 Patient characteristics

From: Vascular miR-181b controls tissue factor-dependent thrombogenicity and inflammation in type 2 diabetes

Patient characteristics
n = 46
Mean ± SD, median [IQR] or percentageCorrelation coefficient vs. miR-181bp-value
Age (years)65.6 ± 9.3− 0.0530.722
Female gender (%)26.00.0110.941
BMI (kg/m2)30.6 [27.75–35.25]0.2030.175
Minimal fasting blood glucose (mg/dL)93.0 [75.75–128.3]− 0.1050.485
Maximal fasting blood glucose (mg/dL)197.5 [140.5–238.8]0.1460.332
Average fasting blood glucose (mg/dL)139.1 [117.8–166.5]− 0.0120.934
HbA1c (%)8.39 ± 1.610.28950.051
HbA1c (mmol/mol)68.1 ± 17.70.28950.051
CRP (mg/dL)0.40 [0.14–0.64]− 0.0510.733
Leukocytes (N/nL)7.4 [6.37–9.12]− 0.2950.045*
Neutrophils (%)59.4 [52.03–66.65]− 0.3180.031*
Monocytes (%)6.83 ± 2.290.0280.850
d-Dimers (ng/mL)377.8 [247.4–523.5]− 0.3430.019*
Hemoglobin (g/dL)14.0 ± 1.2− 0.0890.555
Homocysteine (µmol/L)12.5 [10.95–17.08]0.0710.637
thrombocytes (N/nL)211.9 ± 51.7− 0.2260.130
Triglycerides (mg/dL)186 [110.3–271.0]0.2220.136
LDL cholesterol (mg/dL)113 [88–135]0.0430.796
miR-181b-5p0.169 [0.014–0.470]1 
hypertension (%)100  
CAD (%)41.3− 0.1770.236
PAD (%)26.0− 0.0960.521
carotid stenosis (%)8.6− 0.1330.375
history of stroke (%)10.8− 0.2490.094
History of myocardial infarction (%)15.2− 0.0060.964
Medication
 Insulin (%)69.5− 0.1350.370
 Metformin (%)50.00.462< 0.001*
 Sulfonylurea (%)17.3− 0.1460.330
 Statin (%)50.0− 0.0400.787
 Diuretics (%)60.80.1640.274
 ACE inhibitor (%)47.80.1140.447
 Angiotensin receptor blocker (%)28.20.1940.194
 Aldosterone antagonist (%)8.6− 0.0170.908
 Calcium antagonist (%)17.3− 0.1770.239
 Nitrate vasodilators (%)13.0− 0.0340.822
 Acetylsalicylic acid (%)58.7− 0.0210.886
 Beta-blocker (%)50.00.1940.194
  1. N = 46, shown are either Pearson or Spearman correlation coefficients for normally and not normally distributed continuous variables, respectively. For binary variables, a point-biserial correlation was performed. Values presented are mean ± SD, medians [IQR] or percentages
  2. ACE angiotensin-converting enzyme, BMI body mass index, CAD coronary artery disease, CRP c-reactive protein, HbA1c glycated hemoglobin, LDL low-density lipoprotein, MI myocardial infarction, PAD peripheral artery disease, TF tissue factor
  3. *p<0.05