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Table 2 Baseline characteristics according to status of glucose metabolism

From: Prognostic utility of heart-type fatty acid-binding protein in patients with stable coronary artery disease and impaired glucose metabolism: a cohort study

VariablesTotal (N = 4594)NGR (N = 801)Pre-DM (N = 1904)DM (N = 1889)p value for trend
Baseline characteristics
 Age (years)58.2 ± 9.955.2 ± 9.958.3 ± 9.559.3 ± 9.7< 0.001*
 Male (n, %)3266 (71.9%)617 (77.0%)1346 (70.7%)1303 (69.0%)< 0.001*
 BMI (kg/m2)25.92 ± 3.1425.51 ± 3.0125.69 ± 2.9626.38 ± 3.420.006
 Hypertension (n, %)3005 (65.4%)461 (57.6%)1200 (63.0%)1344 (71.1%)< 0.001
 Dyslipidemia (n, %)4147 (90.3%)701 (87.5%)1745 (91.6%)1701 (90.0%)0.004*
 Current smokers (n, %)1438 (31.3%)332 (41.4%)704 (37.0%)402 (21.3%)< 0.001
 Peripheral vascular disease (n, %)59 (1.3%)6 (0.7%)18 (0.9%)35 (1.9%)0.015
 Cerebrovascular disease (n, %)145 (3.2%)24 (3.0%)60 (3.2%)61 (3.2%)0.951
 Family history of CAD (n, %)643 (14.0%)137 (17.1%)255 (13.4%)251 (13.3%)0.020*
Laboratory data
 Triglyceride (mmol/L)1.80 ± 1.231.67 ± 1.141.73 ± 1.001.93 ± 1.46< 0.001
 TC (mmol/L)4.14 ± 1.174.03 ± 1.034.19 ± 1.174.14 ± 1.22< 0.001*
 LDL-C (mmol/L)2.51 ± 0.992.45 ± 1.012.54 ± 0.972.50 ± 0.950.284
 HDL-C (mmol/L)1.05 ± 0.291.07 ± 0.311.08 ± 0.301.03 ± 0.280.001
 Glucose (mmol/L)6.20 ± 2.044.79 ± 0.425.32 ± 0.657.69 ± 2.41< 0.001*
 HbA1c (%)6.54 ± 1.245.37 ± 0.245.05 ± 0.267.64 ± 1.23< 0.001*
 H-FABP (ng/mL)2.45 ± 1.862.10 ± 1.132.41 ± 1.712.64 ± 2.21< 0.001*
 Creatinine (μmol/L)77.97 ± 17.3078.55 ± 16.2878.40 ± 18.9477.29 ± 15.950.532
 eGFR (mL/min/1.73 m2)93.74 ± 9.1295.77 ± 8.8793.80 ± 8.6492.81 ± 9.56< 0.001*
Treatments in hospital
 Aspirin (n, %)4462 (97.1%)776 (96.9%)1861 (97.7%)1825 (96.6%)0.103
 β-Blokers (n, %)3417 (78.3%)595 (74.3%)1466 (77.0%)1536 (81.3%)< 0.001
 Lipid-lowering mediation (n, %)4269 (92.9%)731 (91.3%)1786 (93.8%)1752 (92.7%)0.058
 ACEI or ARB (n, %)2157 (47.0%)334 (41.7%)877 (46.1%)946 (50.1%)< 0.001
 Gensini score34.50 ± 32.0730.94 ± 28.0232.16 ± 29.5438.38 ± 35.56< 0.001
Events (n, %)380 (8.3%)45 (5.6%)125 (6.6%)210 (11.1%)< 0.001
  1. Values are expressed as the mean ± SD or n (%). Italic values indicate statistical significance. *Indicate statistical significance between NGR and Pre-DM
  2. CAD coronary artery disease, BMI body mass index, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, HbA1c glycated hemoglobin A1c, H-FABP heart-fatty acid binding protein, ACEI angiotensin converting enzyme inhibitors, ARB angiotensin receptor blocker, NGR normal glucose regulation, Pre-DM pre-diabetes mellitus, DM diabetes mellitus, eGFR estimated glomerular filtration rate