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Table 1 Baseline characteristics of patients with different H-FABP levels

From: Prognostic utility of heart-type fatty acid-binding protein in patients with stable coronary artery disease and impaired glucose metabolism: a cohort study

VariablesTotal (N = 4594)Tertile 1 (N = 1685)Tertile 2 (N = 1452)Tertile 3 (N = 1457)p value for trend
Baseline characteristics
 Age (years)58.2 ± 9.954.7 ± 9.158.4 ± 9.262.0 ± 9.7< 0.001
 Male (n, %)3266 (71.9%)1206 (71.6%)1041 (71.7%)1019 (69.9%)0.499
 BMI (kg/m2)25.92 ± 3.1425.82 ± 2.9825.91 ± 3.0826.06 ± 3.360.114
 Hypertension (n, %)3005 (65.4%)1041 (61.8%)917 (63.2%)1047 (71.9%)< 0.001
 Dyslipidemia (n, %)4147 (90.3%)1520 (90.2%)1323 (91.1%)1304 (89.5%)0.337
 Diabetes (n, %)1889 (41.1%)618 (36.7%)566 (39.0%)705 (48.4%)< 0.001
 Current smokers (n, %)1438 (31.3%)548 (32.5%)468 (32.2%)422 (29.0%)0.065
 Peripheral vascular disease (n, %)59 (1.3%)16 (0.9%)19 (1.3%)24 (1.6%)0.222
 Cerebrovascular disease (n, %)145 (3.2%)44 (2.6%)46 (3.2%)55 (3.8%)0.177
 Family history of CAD (n, %)643 (14.0%)258 (15.3%)198 (13.6%)187 (12.8%)0.122
Laboratory data
 Triglyceride (mmol/L)1.80 ± 1.231.82 ± 1.321.80 ± 1.151.78 ± 1.220.581
 TC (mmol/L)4.14 ± 1.174.15 ± 1.204.13 ± 1.094.14 ± 1.200.929
 LDL-C (mmol/L)2.51 ± 0.992.53 ± 1.082.51 ± 0.932.48 ± 0.950.260
 HDL-C (mmol/L)1.05 ± 0.291.05 ± 0.291.06 ± 0.291.06 ± 0.290.506
 Glucose (mmol/L)6.20 ± 2.046.12 ± 2.006.16 ± 1.996.33 ± 2.130.016
 HbA1c (%)6.54 ± 1.246.42 ± 1.226.50 ± 1.176.72 ± 1.30< 0.001
 Creatinine (μmol/L)77.97 ± 17.3074.17 ± 13.9876.23 ± 14.6284.10 ± 21.16< 0.001
 eGFR (mL/min/1.73 m2)93.74 ± 9.1297.38 ± 8.0794.09 ± 8.0989.16 ± 9.24< 0.001
Treatments in hospital
 Aspirin (n, %)4462 (97.1%)1637 (97.2%)1410 (97.1%)1415 (97.1%)0.997
 β-Blokers (n, %)3417 (78.3%)1335 (79.2%)1133 (78.0%)1129 (77.5%)0.477
 Lipid-lowering mediation (n, %)4269 (92.9%)1551 (92.0%)1348 (92.8%)1370 (94.0%)0.096
 ACEI or ARB (n, %)2157 (47.0%)714 (42.4%)669 (46.1%)774 (53.1%)< 0.001
Gensini score34.50 ± 32.0732.42 ± 30.3333.70 ± 30.4437.72 ± 35.24< 0.001
Events (n, %)380 (8.3%)100 (5.9%)121 (8.3%)159 (10.9%)< 0.001
  1. Values are expressed as the mean ± SD or n (%). Italic values indicate statistical significance
  2. CAD coronary artery disease, BMI body mass index, NGR normal glucose regulation, Pre-DM pre-diabetes mellitus, DM diabetes mellitus, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, HbA1c glycated hemoglobin A1c, H-FABP heart-fatty acid binding protein, ACEI angiotensin converting enzyme inhibitors, ARB angiotensin receptor blocker, eGFR estimated glomerular filtration rate